Dr.
Devalina Goswami
Female
Affiliation
Department of
SET Facility
Dr.
Manpreet Kaur
Female
Affiliation
Department of
SET Facility
Dr.
Rashmi Ramachandran
Female
Affiliation
Department of
SET Facility
Dr.
Sujata Mohanty
Female
Affiliation
Professor
Department of
Stem Cell Facility
Contact
Email :
drmohantysujata[at]gmail[dot]com
Phone :
011-26593085
9868398194
Professional Experience and Training relevant to the Project
Membership of the Technical Expert Groups and Consultancy
| 1 | Member of Institute Committee for Stem Cell Research |
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| 2 | Member: International Bodies |
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| 3 | Member of Advisory Bodies |
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| 4 | Member- Research Grant Review Committee |
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| 5 | Member- Journal Review Committee |
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| 6 | Member- Editorial Committee |
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Publications
- Published
- Research Papers: 99
- Abstracts: 88
- Submitted: 15
Patents (filed): 02
Book Chapters:03
- Mohanty S (2016), Cellular Therapy for Ocular Diseases (pp467-478). ThirumurthyVelpandian, Pharmacology of Ocular Therapeutics- Springer Nature, New York. DOI 10.1007/978-3-319-25498-2
- Mohanty S (2016), Regenerative Medicine. D. Prabhakaran, Tandon’s Textbook of Cardiology.(Under review)
- Mohanty S (2016), Clinical trials of cardiac regeneration using adult stem cells: Current and future prospects, Regenerative Medicine: Laboratory to Clinic- Springer Nature (Under review)
Honors/Awards
- University Grant Commission (UGC) fellowship during Ph.D (1991).
- Junior Investigator Prize for best paper (1997).
- Post-Doctoral fellowship from Mount Sinai hospital, New York, USA (1998).
- Award from International Society for Stem Cell Research, USA (three times).
- AIIMS Excellence Award in recognition of notable published research work. (2012, 2014 & 2015).
- Bharat Jyoti Award from India International Friendship Society (2013).
- Third prize for poster presentation in 15th INDO-US Flow Cytometry Workshop on “STEM CELLS’’ , 2014.
- ICMR International Fellowship (2014-2015) for training at Kyoto Prefectural University of Medicine, Kyoto, Japan, in Stem Cells and Scaffolds.
- Best paper award for poster presentation in 43rd Annual Conference of the Indian Immunology Society (2017).
2017
- Evaluating the osteogenic potential of CHT/HAP/PCL biocomposites in bone tissue engineering: An in vivo study. Krishan Gopal Jain, Manisha Singh, Anupama Kakkar, Rajesh Malhotra, Vineeta Batra, Alok Ray, Balram Airan, Mohanty S. International Journal Of Scientific Research (Accepted) https://www.worldwidejournals.com/international-journal-of-scientific-research(IJSR)//articles.php?val=MTA3NTE=&b1=673&k=169
- Bone Marrow stem cell therapy partially ameliorates pathological consequences of liver in mice expressing mutant α1-antitrypsin. Prakash Baligar, Veena Kochat, Shailendra K. Arindkar, Zaffar Equbal, Snehashish Mukherjee, Swati Patel, Perumal Nagarajan, Mohanty S, Jeffrey H. Teckman, Asok Mukhopadhyay (2017 Hepatology. Volume 65, Issue 4, pages 1319–1335, April 2017)https://www.ncbi.nlm.nih.gov/pubmed/28056498
- Hypoxia-mediated epigenetic regulation of stemness in brain tumor cells. Pankaj Prasad, Shivani Mittal, Mohanty S, Tapasya Srivastava. Stem Cells, 2017 STEM2621 (Accepted). https://www.ncbi.nlm.nih.gov/pubmed/28376560
- Differential Reduction of Reactive Oxygen Species by Human Tissue-Specific Mesenchymal Stem Cells from Different Donors Under Oxidative Stress. Paliwal Swati, Kakkar Anupama, Rinkey Sharma, Airan Balram, Mohanty S (2017) Journal of BioSciences -D-16-00538R1 (Accepted)
2016
- Fabrication of transparent quaternized PVA/silver nanocomposite hydrogel and its evaluation as an antimicrobial patch for wound care systems. Bhowmick, S., Mohanty, S. & Koul, V. (2016). J Mater Sci: Mater Med (2016) 27: 160. doi:10.1007/s10856-016-5772-8.https://www.ncbi.nlm.nih.gov/pubmed/27638099
- Effect of Hypoxia on Stemness and Differentiation of Dental Pulp Derived Stem Cells.Anupama Kakkar, Puneet Sharma, Manimuthu Mani Sankar, OP Kharbanda, Mohanty S* IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) olume 15, Issue 8 Ver. VII (August. 2016), PP 102-111, http://www.iosrjournals.org/iosr-jdms/papers/Vol15-Issue%208/Version-7/T150807102111.pdf
- Can Mesenchymal Stem Cell be used as an Additive Therapeutic Procedure for Fracture Healing in Facial Injuries??Ruchi Pathak Kaul, Sushma Sagar, Mohanty S, Subodh Kumar (2016). Journal of Dental and Oral Health Volume 2 • Issue 4 • e106
- Feeder and bFGF free culture of human embryonic stem cells: Role of conditioned media from immortalized human feedersPooja Teotia, Mohanty S*, Shilpa Sharma, Balram Airan;c Manuscript ID: IJMR_152015-0472(424-15) (Accepted). https://www.ncbi.nlm.nih.gov/pubmed/28474621
- Evaluation of sterilization of contaminated donor corneas by Gamma irradiation. Himi Tripathi, Pratik Kumar, Deepika Gupta, Rebika Dhiman, SeemaSen, SeemaKashyap, Tapas Nag, GeetaSatpathi, Mohanty S*, RadhikaTandon. IOVS Manuscript ID: IOVS-15-18223 (Accepted)
- Hair and Skin derived Progenitor Cells: In Search of a Candidate Cell for Regenerative Medicine Anil Kumar, Mohanty S*, Sushmita Bose Nandy, Somesh Gupta, Binod K Khaitan, Shilpa Sharma, BalramBhargava, BalramAiran .Indian J Med Res 2016 Feb;143(2):175-83.https://www.ncbi.nlm.nih.gov/pubmed/27121515
- Report: Stem cell applications in neurological practice, an expert group consensusappraisal. Devi M G, Sharma A, Mohanty S, Jain N, Verma K, Padma M V, Pal P, Chabbra H S, Khadilkar S, Prabhakar S, Singh G. Ann Indian Acad Neurol 016;19:367-73. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980961/
- Evaluation of circulating haematopoietic progenitor cells in patients with Trauma Haemorrhagic shock and its correlation with outcomes. umar M, Bhoi S, Subramanian A, Kamal VK, Mohanty S, Rao D, Galwankar S. Int J Crit Illn In jSci 2016;6:56-60. https://www.ncbi.nlm.nih.gov/pubmed/27308251
- Long Term Preservation of Donor Corneas in Glycerol for Keratoplasty: Exploring New Protocols.HimiTripathi, ,ManzoorUl Mehdi, Deepika Gupta, SeemaSen, SeemaKashyap,Tapas Chandra Nag, ManishaPurwar, ManjeetJassal, Ashwini K Agrawal, MohantyS*, Radhika Tandon. Br J Ophthalmol 2016 Feb;100(2):284-90. http://bjo.bmj.com/content/early/2015/10/26/bjophthalmol-2015-306944
2015
- Stem Cells of the Hair Follicular Tissue: Application in Cell Based Therapy for Vitiligo. Kumar A, Mohanty S, Gupta S, Paulkhurana SM (2015) Hair Ther Transplant :132. doi:10.4172/2167-0951.1000132. https://www.omicsgroup.org/journals/stem-cells-of-the-hair-follicular-tissue-application-in-cell-based-therapyfor-vitiligo-2167-0951-1000132.php?aid=47699
- Culture & differentiation of Mesenchymal Stem Cell into osteoblast on degradable biomedical composite scaffold: In vitro study. ain KG, Mohanty S, Ray AR, Malhotra R, Airan B. Indian J Med Res 2015 Dec;142(6):747-58. https://www.ncbi.nlm.nih.gov/pubmed/26831424
- “An invention of thermo-responsive polymer surface, yielding cell sheet based regenerative therapies in cardiology and ophthalmology” Sawa Y , Cherian KM , Mohanty S , Ganesh JS , Abraham S Journal of Stem cells and Regenerative medicine 2015 JSRM Code: 011020700010. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728217/
- Long Term Outcomes of Cultivated Limbal Epithelial Transplantation: Evaluation and Comparison of Results in Children and Adults Anita Ganger, M. Vanathi, Mohanty S , Radhika Tandon;; BioMed Research International vol. 2015, Article ID 480983, 6 pages, 2015. doi:10.1155/2015/480983. https://www.hindawi.com/journals/bmri/2015/480983/
- Efficacy of stem cell in improvement of left ventricular function in acute myocardial infarction - mi3 trial; elu Nair, Hemant Madan, Sunil Sofat, ProsenjitGanguli, M.J. Jacob, Rajat Datta, Prashant Bharadwaj, R.S. Sarkar, A.J. Pandit, Soniya Nityanand, Pravin K. Goel, Naveen Garg, Sanjay Gambhir, Paul V. George ,Sunil Chandy, Vikram Mathews, Oomen K. George, K.K. Talwar, Ajay Bahl, Neelam Marwah, Anish Bhatacharya, Balram Bhargava, Balram Airan, Mohanty S, Chetan D. Patel, Alka Sharma,Shinjini Bhatnagar, A. Mondal, Jacob Jose, A. Srivastava; IJMR 2015 ;142(2):165-74. https://www.ncbi.nlm.nih.gov/pubmed/26354213
- Enhanced reprogramming efficiency and kinetics of induced pluripotent stem cells derived from human duchenne muscular dystrophy; PoojaTeotia, Mohanty S*, Madhulika Kabr, Sheffali Gulati, Balram Airan; PLOS Currents: Muscular Dystrophy; ersion 1. PLoSCurr. 2015 September 3; 7. https://www.ncbi.nlm.nih.gov/pubmed/26579330
- Role of Human Cardiac biopsy derived Conditioned Media in modulating Bone Marrow derived Mesenchymal Stem Cells towards Cardiomyocyte like Cells; Anupama Kakkar, Mohanty S*, BalramBhargava, BalramAiran; July,2015; Journal of Practice of Cardiovascular Sciences; 015; 1(2):150-155. http://www.j-pcs.org/article.asp?issn=2395-5414;year=2015;volume=1;issue=2;spage=150;epage=155;aulast=Kakkar
- Evaluation of serum granulocyte colony stimulating factors in patients admitted with Trauma Haemorrhagic shock and their correlation with immediate outcome.Manoj Kumar, Sanjeev Bhoi, S. Arul Selvi, Vineet Sharma, Mohanty S, D. N. Rao Int. J. Adv. Res. Biol.Sci 2(7): (2015): 107–114. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901827/
- Interleukin (IL)-8 is an early predictor of mortality following trauma hemorrhagic shock ; Manoj Kumar, D.N Rao, Mohanty S, Arul Selvi S, SanjeevBhoi; Int. J. Adv. Res. Biol.Sci 2(7): (2015): 12–20. https://www.omicsonline.org/proceedings/interleukin-il8-early-predictor-of-mortality-following-trauma-hemorrhagic-shock-29282.html
- Strategies for faster detachment of corneal cell sheet using micropatterned thermo-responsive matrices.Sharda Nara, Shibu Chameettachal, Swati Midha, Himi Singh, Radhika Tandon, Mohanty S, Sourabh Ghosh J. Mater. Chem. B 015,3, 4155-4169. http://pubs.rsc.org/en/Content/ArticleLanding/2015/TB/c5tb00350d#!divAbstract
2014
- Detection of homing-in of stem cells labeled with technetium-99m hexamethylpropyleneamineoxime in infarcted myocardium after intracoronary injection. Patel CD, Agarwal S, Seth S, Mohanty S*, Aggarwal H, Gupta N. Indian J Nucl Med 2014 Oct;29(4):276-7. doi: 10.4103/0972-3919.14264. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228599/
- Fibroblast Growth Factor-2 alone as an efficient inducer for differentiation of human bone marrow mesenchymal stem cells into dopaminergic neurons.Sushmita Bose, Mohanty S*, Manisha Singh, MadhuriBehari, BalramAiran Journal of Biomedical Science nbsp;2014, 21:83 doi:10.1186/s12929-014-0083-1 https://www.ncbi.nlm.nih.gov/pubmed/25248378
- Intravenous autologous bone marrow mononuclear cell therapy for ischemic stroke: A multi-centric, randomized trial. Kameshwar Prasad, Alka Sharma, Ajay Garg, Mohanty S, Shinjini Bhatnagar, Sharat Johri, KK Singh, Velu Nair, Ravi Sarkar, Sankar Gorthi, Kaukab Hassan, Sudesh Prabhakar, Neelam Marwaha, Niranjan Khandelwal, Usha Misra, Jayantee Kalita, and Soniya Nityanand. Stroke 2014/007028D-AR1. https://www.ncbi.nlm.nih.gov/pubmed/25378424
- Autologous stem cell transplantation in refractory Asherman's syndrome: A novel cell based therapy. Neeta Singh, MohantyS*, Tulika Seth, Meenakshi Shankar, Sruthi Bhaskaran, Sona Dharmendra. J Hum Reprod Sci 2014 Apr-Jun; 7(2): 93–98. https://www.ncbi.nlm.nih.gov/pubmed/25191021
- Stem cells in Neurological Diseases: Indian perspective. Ashu Bhasin, Padma Srivastava MV, Rohit Bhatia, Senthil Kumaran, Mohanty S.J Stem Cell Res Ther 2014, 4:3 (http://dx.doi.org/10.4172/2157-7633.1000175). https://www.omicsonline.org/open-access/review-stem-cells-in-neurological-diseases-indian-perspective-2157-7633.1000175.php?aid=23627
- Effect of stem cells on renal recovery in rat model of partial unilateral upper ureteric obstruction. N. Sugandhi, M. Srinivas, S. Agarwala, D. K. Gupta, S. Sharma, A. Sinha, A. Dinda, S. Mohanty Pediatric surgery International, 2014. 30:233–238. https://www.ncbi.nlm.nih.gov/pubmed/24370792
- Surface-Modified Electrospun Poly (e-Caprolactone) Scaffold With Improved Optical Transparency and Bioactivity for Damaged Ocular Surface Reconstruction.Shweta Sharma, Deepika Gupta ,Mohanty S, ManjeetJassal, Ashwini K. Agrawal , RadhikaTandon. Invest Ophthalmol Vis Sci. 2014; 55:899–907. DOI:10.1167/ iovs.13-12727. https://www.ncbi.nlm.nih.gov/pubmed/24425860
- 5-Florouracil-loaded poly(lactic acid)-poly(caprolactone) hybrid scaffold: potential chemotherapeutic implant. Gupta KK, Pal N, Mishra PK, Srivastava P, Mohanty S, Maiti P. .J Biomed Mater Res A. 014 Aug;102(8):2600-12. https://www.ncbi.nlm.nih.gov/pubmed/24038786
2013
- Propitious role of Bone marrow-derived mononuclear cells in an Experimental Bile Duct Ligation model - Potential clinical implications in obstructive cholangiopathy. Shilpa Sharma, Mohanty S*, Prasenjit Das, Sidhartha Dutta Gupta, Lalit Kumar, evendra Gupta.. Pediatric surgery International, 013 Jun;29(6):623-32. https://www.ncbi.nlm.nih.gov/pubmed/23604400
- Depletion of CD200+ bulge stem cells in premature human gray hair follicles. Mohanty S*, Anil Kumar, Somesh Gupta. J Cutan Aesthet Surg 2013 Apr-Jun; 6(2): 90–92. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764768/
- Stem Cell Niche is Partially Lost during Follicular Plucking: A Preliminary Pilot Study.Kumar A, Gupta S, Mohanty S, Bhargava B, Airan B. Int J Trichology 2013 Apr;5(2):97-100. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877484/
- Extracted hair follicle outer root sheath cell suspension for pigment cell restoration in vitiligo.Kumar A, Mohanty S, Sahni K, Kumar R, Gupta SJ Cutan Aesthet Surg 2013 Apr;6 (2):121-5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764761/
- Limbal Epithelial stem cells in Corneal Regeneration Shweta Sharma, M Vanathi, Mohanty S, RadhikaTondon.Delhi Journal of Opthalomology;2013; 24(1:43-50).http://www.djo.org.in/articles/24/1/Limbal-Epithelial-Stem-Cells-in-Corneal-Regeneration.html
- TGF-beta1 contribues to cardiomyogenic like differentiation of human bone marrow Mesenchymal Stem Cells. Mohanty S, Sushmita Bose, KrishanGopal Jain, Balram Bhargava, Balram Airan.International Journal of Cardiology 2013 Feb 10;163(1):93-9. https://www.ncbi.nlm.nih.gov/pubmed/21903280
Dr.
Karthikeyan P
Male
MD, PhD
Affiliation
Department of
Biochemistry
Contact
Email :
karthikeyan_p[at]aiims[dot]edu
Office Address
Address : Room No: 3013 (Seminar Room), Department of Biochemistry,
3rd Floor Teaching Block, AIIMS, New Delhi – 110029
Public profiles:
Orcid | Google Scholar | Research Gate | YouTube | Goodreads
Academic Qualifications:
| Sr. No. | Degree | Year | Subject | University/Institution |
|---|---|---|---|---|
| 1. | MBBS | 2010 | All Subjects | Kanyakumari Government Medical College |
| 2. | MD | 2015 | Biochemistry | Maulana Azad Medical College |
| 3. | DNB | 2016 | Biochemistry | National Board of Examinations |
| 4. | PhD | 2022 | Biochemistry | AIIMS, New Delhi |
Work Experience:
| Sr. No. | Positions held | Name of the Institute | Period |
|---|---|---|---|
| 1 | Junior Resident | Maulana Azad Medical College | 2012 - 2015 |
| 2 | Senior Resident | AIIMS, New Delhi | 2015 - 2018 |
| 3 | Research Associate II | AIIMS, New Delhi | 2019 - 2022 |
| 4 | Assistant Professor | Maulana Azad Medical College | May 2022 – Jan 2023 |
Book and Book Chapters:
- Biochemistry For Undergraduates, First Edition, CBS Publishers (ISBN – 9789388725972)
- Eleven chapters in Springer - Nature publication, Encyclopaedia of Animal Cognition and Behaviour
Memberships:
- Member of National Academy of Medical Sciences, India (MNAMS)
- Life member of Association of Medical Biochemists of India (AMBI)
- Life Member of Clinical Biochemists of India (ACBI)
- Life Member of Indian Immunology Society
Positions Available in the Lab:
If you are interested in working on similar projects as ours or have a unique idea in any field that you wish to pursue, please send an email to karthikeyan_p[at]aiims[dot]edu.People with independent fellowships are welcomed. Let's explore opportunities for collaboration and growth together.
Professional Recognition/Award/ Prize/Certificate:
| Sr. No | Name of Award | Awarding Agency | Year |
|---|---|---|---|
| 1 | FIRST PRIZE in Biochemistry Quiz Competition | Association of Medical Biochemists of India | 2014 |
| 2 | Certificate for BEST JOURNAL CLUB PRESENTATION | Dept. of Biochemistry, AIIMS, Delhi | 2017 |
| 3 | Acknowledgement in Harper illustrated Biochemistry, 31st edition for suggestions and corrections | Victor W. Rodwell (chief editor) | 2018 |
| 4 | Research Associate Fellowship | Indian Council of Medical Research | 2019 |
| 5 | Certificate for Quiz Master | Indian Immunology Society | 2020, 2021, 2022 |
Research focus
Leukemia Biology, Bioinformatics, Medical Education
Publications (PubMed indexed only):
| Sr. No | Author(s) | Title | Name of Journal | Volume | Page | Year |
|---|---|---|---|---|---|---|
| 1 | Pethusamy K, Seethy A, Dhar R, Karmakar A, Chaudhary S, Bakhshi S, P JK, Chopra A et al. | Loss of TET2 with reduced genomic 5-hmC is associated with adverse-risk AML | Leukemia & lymphoma | 63(14) | 3426-3432 | 2022 |
| 2 | Sahoo OS, Pethusamy K, Srivastava TP, Talukdar J et al. | The metabolic addiction of cancer stem cells. | Frontiers in oncology | 12:955892. | eCollection | 2022 |
| 3 | Chattopadhyay I, Dhar R, Pethusamy K, Seethy A et al. | Exploring the Role of Gut Microbiome in Colon Cancer | Applied Biochemistry and Biotechnology | 193(6) | 1780-1799 | 2021 |
| 4 | Seethy A, Pethusamy K, Chattopadhyay I, Sah R et al. | TETology: Epigenetic Mastermind in Action | Applied Biochemistry and Biotechnology | 193(6) | 1701-1726 | 2021 |
| 5 | Dhar R, Seethy A, Singh S, Pethusamy K, Srivastava T et al. | Cancer immunotherapy: Recent advances and challenges. | Journal of Cancer Research and Therapeutics | 17(4) | 834-844 | 2021 |
| 6 | Dhar R, Singh S, Mukherjee I, Pethusamy K, Purkayastha K et al. | EMTiness in pseudo-malignant behavior of trophoblasts during embryo implantation. | Frontiers in Bioscience-Landmark | 26(4) | 717-743 | 2021 |
| 7 | Seethy AA, Singh S, Mukherjee I, Pethusamy K et al. | Potential SARS-CoV-2 interactions with proteins involved in trophoblast functions - An in-silico study. | Placenta | 103 | 141-151 | 2021 |
| 8 | Chakraborty M, Singh P, Dsouza JMP, Pethusamy K et al. | Fasting and postprandial lipid parameters: A comparative evaluation of cardiovascular risk assessment in prediabetes and diabetes. | J Family Med Prim Care | 28;9(1) | 287-292 | 2020 |
| 9 | Dhar R, Pethusamy K, Singh S, Mukherjee I et al. | Draft genome of Ompok bimaculatus (Pabda fish). | BMC Research Notes | 26;12(1) | 825 | 2019 |
| 10 | Dhar R, Seethy A, Pethusamy K, Singh S et al. | De novo assembly of the Indian blue peacock (Pavo cristatus) genome using Oxford Nanopore technology and Illumina sequencing. | Gigascience | 1;8(5) | giz038 | 2019 |
Dr.
Siddhartha Kundu
Male
MD, PhD
Affiliation
Associate Professor
Department of
Biochemistry
Contact
Email :
siddhartha_kundu[at]aiims[dot]edu
Phone :
+91-11-26546514
Areas of Interest
Mathematical analyses of biochemical reactions & metabolic networks Mathematical modelling and simulations of complex biochemical systems Algorithms for molecular biology
Servers/Software developed
| Hyperlink | Description |
|---|---|
| http://doi.org//10.1142/S0219720022500184 https://cran.r-project.org/package=TemporalGSSA | [Siddhartha_kundu_img1.png] |
| http://doi.org//10.3389/fmolb.2023.1206502 https://cran.r-project.org/package=ReDirection | [Siddhartha_kundu_img2.png] |
| http://doi.org//10.1177/11779322211045878 http://178.63.18.214/ProTG4.html | [Siddhartha_kundu_img2.png] |
| http://doi.org/10.1186/s13104-021-05477-z http://178.63.18.214/Fe2OG.html | [Siddhartha_kundu_img2.png] |
Educational qualifications
| Degree | Subject | University/Institution | Year |
|---|---|---|---|
| PhD | Computational Biology & Bioinformatics | School of Computational and Integrative Sciences (SCIS), Jawaharlal Nehru University, New Mehrauli Road, New Delhi 110067 | 2014-2018 |
| MD | Biochemistry | All India Institute of Medical Sciences (AIIMS), Ansari Nagar, New Delhi 110029 | 1999-2001 |
| MBBS | Pre-&Para-/Medical/ Surgical subjects | University College of Medical Sciences (UCMS), Dilshad Garden, New Delhi 110095 | 1992-1996 |
Memberships
| 1. | Society for Mathematical Biology (SMB): Life member (ID:36503496) |
| 2. | European Society for Mathematical and Theoretical Biology (ESMTB) : Life member ID: 50143836 |
| 3. | Elected member Sigma Xi society ( Scientific Research Honors Society) |
Positions held
| Position | Subject/Work | University/Institution | Year |
|---|---|---|---|
| Associate Professor Assistant Professor | Biochemistry | All India Institute of Medical Sciences (AIIMS), Ansari Nagar, New Delhi 110029 | 2023-2019-2023 |
| Associate Professor | Biochemistry | Army College of Medical Sciences (ACMS), Dr. Baba SahebAmbedkar Medical College and Hospital (BSAMCH), Govt. of NCT of Delhi, Rohini, Delhi 110085 | 2015-2018 2018-2019 |
| Assistant Professor | Biochemistry | Army College of Medical Sciences (ACMS), Brar Square, Delhi Cantt.,New Delhi – 110010 | 2009-2014 |
| Scientist ‘D’ (Medical) | Program Officer | Indian Council of Medical Research (ICMR), V. RamalingaswamiBhawan, Ansari Nagar, New Delhi 110029 | 07-10/2019 |
| Senior Level Consultant | Program Director | Information Technology Research Academy (ITRA), Digital India Corporation (formerly Media Lab Asia), Ministry of Electronics and Information Technology, C-DOT campus, New Delhi 110030 | 2016-2017 |
| Research Consultant | Computational Biology | India Research Labs (IRL) IBM | 2002-2003 |
Research Associate/Fellow/Scientist
| PostDoctoral work | International Center for Genetic Engineering and Biotechnology (ICGEB) National Institute of Immunology (NII) ICMR-National Institute of Pathology (NIOP) Indian Institute of Technology Delhi (IITD) | 05-10/2014 2005-2008 2003-2004 01-05/2002 |
Award/recognition:
AIIMS excellence research award (Certificate of commendation)
| 1. | 2022 | Kundu S#*. TemporalGSSA: a numerically robust R-wrapper to facilitate computation of a metabolite-specific and simulation time-dependent trajectory from stochastic simulation algorithm (SSA)-generated datasets. Jour Bioinf. Comp. Biol. 2022, 20(4):2250018. PMID: 35941839 JBCB2022 (Additional Material). |
| 2. | 2021 | Kundu S#*. Mathematical modeling and stochastic simulations suggest that low-affinity peptides can bisect MHC1-mediated export of high-affinity peptides into “early”- and “late”-phases. Heliyon. 2021, 7(7):e07466. PMID: 34286133 [HYON2021] (Additional Material). |
Research publications (complete citations)
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| (#) Single author; (*)Corresponding author |
Public profiles:
Orcid || Loop-Frontiers || Exaly || ResearchGate || GoogleScholar ||
Dr.
Rakhee Yadav
Female
Affiliation
Additional Professor
Department of
Biochemistry
Contact
Email :
rakheeyadav79[at]gmail[dot]com
Academic Details
| Degree | University/ Institution | Year of Passing |
|---|---|---|
| MBBS | Pt BD Sharma PGIMS, MD University, Rohtak (Haryana) | 2002 |
| MD (Biochemistry) | Pt BD Sharma PGIMS, Pt BD Sharma UHS, Rohtak (Haryana) | 2011 |
Positions held (starting from the most recent):
| Position | Department | University/ Institution | Period |
|---|---|---|---|
| Associate Professor | Biochemistry | AIIMS Delhi | 2020 onwards |
| Assistant Professor | Biochemistry | AIIMS Delhi | 2016-2020 |
| Assistant Professor | Biochemistry | SGT Medical College & Hospital, Gurgaon (Haryana) | 2014-2016 |
| Senior Resident | Biochemistry | VMMC & Safdarjung Hospital Delhi | 2011-2014 |
Research Focus of the Lab/ Key Areas: Adipocyte Biology, Insulin Resistance, Obesity & metabolic syndrome
Projects & Funding: ICMR Extramural and AIIMS Intramural Grants
List of Lab members:
1. Mr Blessed Raj (PhD Scholar):
Mr Blessed Raj has done MSc in Medical Biochemistry from JIPMER Puducherry and got registered as PhD scholar at AIIMS in Nov 2020. His proposed work is to elucidate the role of ECM-Adipocyte communication in obesity induced adipose tissue dysfunctions
2. Dr Astha Sachan (Senior Resident):
Has done MD Thesis under my supervision titled, “Study of ECM Remodeling in adipose tissue dysfunctions in obesity” and presently working in ongoing lab projects.
She has won Mrs. Dwarka Prasad Trust Travel Grant in 2019 to present her work at 15th Asia Pacific Federation for Clinical Biochemistry and Laboratory Medicine (APFCB) Congress; Jaipur in Nov 2019
Also won best oral paper award in AMBION 2020: National Postgraduate Update cum CME, Chandigarh, November, 2020 (Online Presentation)
3. Dr Kuntal Chakraborty (Final year MD Student):
Thesis title “A prospective study of changes in human Gut Microbiota (GM) and its association with insulin sensitivity in obese individuals undergoing Bariatric Surgery”
He has been awarded ICMR financial support for his MD thesis (Dec 2020)
4. Dr Prachi Priyadarshini (Final year MD student):
Thesis title “Study of the expression of vascular endothelial growth factor (VEGF-A) and its isoforms, in Obesity and their association with insulin sensitivity”
5.Dr Khushboo Sharma (Second year MD student):
Thesis titled “Assessment of Amphiregulin and CRISPLD1 as visceral adipose tissue derived modulators of cardiovascular health in obesity”
Research Focus of the Lab/ Key Areas: Adipocyte Biology, Insulin Resistance, Obesity & metabolic syndrome
Projects & Funding: ICMR Extramural and AIIMS Intramural Grants
List of Lab members:
1. Mr Blessed Raj (PhD Scholar):
Mr Blessed Raj has done MSc in Medical Biochemistry from JIPMER Puducherry and got registered as PhD scholar at AIIMS in Nov 2020. His proposed work is to elucidate the role of ECM-Adipocyte communication in obesity induced adipose tissue dysfunctions
2. Dr Astha Sachan (Senior Resident):
Has done MD Thesis under my supervision titled, “Study of ECM Remodeling in adipose tissue dysfunctions in obesity” and presently working in ongoing lab projects.
She has won Mrs. Dwarka Prasad Trust Travel Grant in 2019 to present her work at 15th Asia Pacific Federation for Clinical Biochemistry and Laboratory Medicine (APFCB) Congress; Jaipur in Nov 2019
Also won best oral paper award in AMBION 2020: National Postgraduate Update cum CME, Chandigarh, November, 2020 (Online Presentation)
3. Dr Kuntal Chakraborty (Final year MD Student):
Thesis title “A prospective study of changes in human Gut Microbiota (GM) and its association with insulin sensitivity in obese individuals undergoing Bariatric Surgery”
He has been awarded ICMR financial support for his MD thesis (Dec 2020)
4. Dr Prachi Priyadarshini (Final year MD student):
Thesis title “Study of the expression of vascular endothelial growth factor (VEGF-A) and its isoforms, in Obesity and their association with insulin sensitivity”
5.Dr Khushboo Sharma (Second year MD student):
Thesis titled “Assessment of Amphiregulin and CRISPLD1 as visceral adipose tissue derived modulators of cardiovascular health in obesity”
Dr.
Pramod Kumar Gautam
Male
Affiliation
Additional Professor
Department of
Biochemistry
Contact
Email :
gautam[at]aiims[dot]edu
Phone :
(O) 011-26594682; (Ext) 4682
Office Address
Room No. 3040, 3rd Floor, Teaching Block,
Department of Biochemistry
All India Institute of Medical Sciences
Ansari Nagar, New Delhi-110029
Academic carrier
I am currently working as an additional professor in the Department of Biochemistry. My PhD and post-doctoral fellowship from Banaras Hindu University, Varanasi, India
Academic Activity
UG, PG teaching, and research
Administrative Positions/Activities
- Member of the transport committee, AIIMS, New Delhi
- Worked as a nodal officer for COVID control
- Ph.D. course work in charge
Membership in the Society
- Life member of the Indian Immunology Society, India
- Life Member of Cancer Immunotherapy (CIMT), Germany
- Indian Academy of Biomedical Sciences (IABS)
- The Indian Association of Cancer Research (IACR)
- Association of Clinical Biochemistry (ACBI)
Reviewer and Editorial Board Membership
- The International Journal of Gastrointestinal Cancer
- Journal of Nano particle research (2016 onward)
- Journal of Leukemia Research (2016 onward)
- BMC Cancer
Research Work: - Laboratory of Immunology and Cancer Immunotherapy
The immune system can be likened to a sophisticated army, equipped with various tools and mechanisms to protect the body from infections and cancers. However, during tumor development, cancer cells release substances that suppress the immune system, allowing the tumor to grow and spread. To combat this, researchers are focusing on developing immunotherapies that enhance the body's natural defenses against cancer. These immunotherapies target specific pathways involved in tumor growth, angiogenesis, and immune suppression. By discovering and studying the effects of natural compounds and plant extracts, scientists hope to develop safe and effective treatments for cancer that can be used in combination with existing therapies. The goal is to improve cancer management, early detection, and targeted drug delivery to prevent the progression of the disease. Our research lab utilizes advanced molecular & immunological techniques.
Extramural and Intramural Project:-
- Elucidating the targeted, therapeutic role of docetaxel-loaded-HSP70 peptide complex in PDX Mouse Models. (PI, Ongoing, ICMR)
- Role of M1 macrophage on DNA methylation and PI3K-AKT Signaling Pathway analysis in tumor-associated mesenchymal stem cells in Breast cancer.(PI, Ongoing, AIIMS)
- Development of anti-proliferative agent form boerhaabia diffusa and citrullus colocynthis plant extract in human bladder cancer. (PI, Ongoing, AIIMS)
- Role of Macrophage in the regulation of Bone and Blood forming stem cell and progenitor cells migration and development. (PI, Completed, DBT)
- Evaluation of tumor-derived exosomes in blood during pre and post treatment of pancreatic cancer patients(PI, Completed, AIIMS)
- Development of targeted drug delivery using liposomes/nanoparticles on cancer stem cell using herbal plant extract and hsp70- tumor antigen and to evaluate its anti-tumor function. (PI,SERB, Completed)
- To emphasis the role of macrophage phenotype on mesenchymal stem cell in breast cancer. (Completed, AIIMS)
- To study the role of β-defensin on stem cells, cancer stem cells remodelling and its associated microenvironments(AIIMS, Completed)
Group members:-
- PhD thesis: completed-2; ongoing-1
- MD Thesis: Completed-1; ongoing-1
- Post Doc Fellow-1,
- Research Scientist: 1 (an ICMRfunded project)
- TARE, SERB, New Delhi—Dr. Qulsum Akhtar.
- Project Staff: 2
Current lab members: Miss Anita (CSIR-JRF); Rupinder Kaur (CSIR-SRF, NET), Dr. Sreekar; Dr. Neha Singh; Dr. Soni Kumari (Research Scientist-II); Ankit Kumar; and Bharta Sinha (DEO, AIIMS, New Delhi).
- Miss Anita
Anita submitted her thesis in the year 2024. Her title of thesis is to elucidate the immunomodulatory and anti-tumor role of m1 macrophage on bone marrow derived mesenchymal stem cells: implications in breast cancer. Anita has been qualified CSIR-JRF and currently working as a research scientist in the Dept. of Pharmacology at AIIMS, New Delhi.
- Rupinder Kaur
ORCID: 0000-0002-0158-8307
Rupinder Kaur, a 4th year Ph.D. student (2020-present) and CSIR-SRF (Direct) fellow, delves into the fascinating world of cancer-immunology. Her research focuses on unraveling the immunomodulatory effects of tumor-derived exosomes on Gamma-Delta T cells. By exploring this intricate interaction, she aims to uncover potential therapeutic strategies for cancer treatment. Rupinder's work primarily consists of the analysis of differential micro-RNA cargo in extracellular vesicles in peripheral blood of cancer patients. She is also working on elucidating the mysteries of the change in polarity of gamma delta T cells under the effect of tumor derived extracellular vesicles. She completed her Master in Biochemistry in 2019 from Punjab Agricultural University, Ludhiana.
Thesis Title: “To study the immunomodulatory effect of tumor derived exosomes in Gamma-Delta T cells.”
- Ankit Kumar
Myself, Ankit Kumar and I have done my B.Sc. in Zoology (Hons) from St. Xavier College Ranchi in 2018–21. and currently I have joined as M.Sc student and am working on a thesis titled "Differentially expressed exosomal miRNA derived from Pancreatic Ductal AdenoCarcionoma (PDAC)".
- Neha Singh
Qualification- PhD in Microbiology
ORCID-https://orcid.org/0000-0001-9802-0445
Current affiliation- Project Student, Department of Biochemistry, All India Institute of Medical Sciences
Project Title-Elucidating the targeted therapeutic role of docetaxel- loaded- HSP70 peptide complex in PDX mouse models.
Expertise- Expert in microbiology, medicinal plants, and cancer biology. Skilled in analyzing microbial interactions, identifying medicinal compounds in plants, and studying cancer cell signaling pathways. Proficient in microbiological techniques, plant extraction methods, and cancer cell culture assays. Experience in research, drug discovery, and contributing to advancements in medical science.
- Soni Kumari (Research Scientist II)
PhD in Biochemistry
ORCID ID: 0000-0002-9743-3202
I am currently working as a Research Scientist II on an ICMR-funded project titled “Elucidating the Therapeutic Role of Docetaxel-Loaded HSP Peptide Complex in PDX Mouse Model.”
- Dr. K. V. Sreekar ( MD student)
He has a strong interest in cancer and cancer immunology and is about to embark on research in breast cancer immunology. His focus will be on developing new methods to detect novel biomarkers that can aid in the early diagnosis of breast cancer. He has finished his M.B.B.S. from Dr. NTR university of health sciences, Andhra Pradesh.
Previous Student:-
Dr. Sonam Agarwal (ICMR- RA);Dr.. Khuswant Singh (CSIR-JRF); Dr. Kunal Kumar; Dr. Vijay Mohan (Post Doc Fellow); Pavit Singh (MBBS-STS student).
- Sonam Agarwal:- complete her work on “Detection of prostate cancer biomarker using sensitive and rapid lateral flow device with diagnostic and prognostic significance” (ICMR-RA)
- Khushwant Singh:- Submitted his thesis on Determining the immunomodulatory and antitumor function of hsp70 chemotherapeutic drug conjugates on cancer stem cells
- Marilyn Masih:-Completed her thesis on “Comparative analysis between different stage Cancer patients to discover Novel Blood – based biomarkers for detection of early stage breast cancer- A pilot study”
- Pavit Singh (MBBS-STS student) “To study the differential exosomal abundance in pancreatic cancer patients”
Publication Details
https://orcid.org/0000-0001-7580-8846
https://scholar.google.co.in/citations?user=PBcBKhwAAAAJ&hl=en
https://scholar.google.co.in/citations?user=PBcBKhwAAAAJ&hl=en
Dr.
Riyaz Ahmad Mir
Male
Affiliation
Additional Professor
Department of
Biochemistry
Contact
Email :
riyaz978[at]gmail[dot]com
Phone :
(O) 011-26593706 (Ext) 3706
Office Address
Address: Room No 3040, 3rd Floor, Teaching block,
Department of Biochemistry
All India Institute of Medical Sciences
Ansari Nagar, New Delhi-110029
Employment record:
| Additional Professor | Biochemistry, AIIMS, New Delhi | 2023- present |
| Associate Professor | Biochemistry, AIIMS, New Delhi | 2020-2022 |
| Assistant Professor | Biochemistry, AIIMS, New Delhi | 2016-2020 |
Research Experience:
| Postdoc Fellow | University of Nebraska Medical Center, USA | 2011-2016 |
| PhD | Biochemistry, AIIMS, New Delhi | 2005-2011 |
Reviewer and Editorial Board Member:
- Frontiers in Oncology
- GENE
- Editorial board member Translational pathology and Laboratory medicine
Editorial board member Clinical pathology and research Journal
Research focus of the lab:
We are a dedicated team of researchers focused on understanding the role of the R2TP complex in malignancy. The R2TP complex is a co-chaperone of Hsp90, involved in the assembly and stabilization of various macromolecular complexes in the cell. The interactions and collaborative functions of the R2TP complex with its clients remain poorly understood and unexplored. Our research delves into the molecular associations of the complex whilst cancer progression and how it can potentially be targeted for therapeutic interventions.
Additionally, we explore the functions of tumour suppressors, crucial proteins that play a pivotal role in preventing the uncontrolled growth of cancer cells. Understanding how these proteins operate and how they can be manipulated is a key aspect of our work.
Furthermore, our lab is also interested in the effects of genetic manipulation in mammalian inner ear cells. This area of research is important for understanding hearing loss and other inner ear disorders, and it has implications for the development of potential treatments.
We are committed to advancing knowledge in these areas and contributing to the development of novel strategies for treatment. To learn more about our ongoing projects and recent discoveries, please email
L to R: Ayesha, Pankaj, Hema, Dr Riyaz, Dhiraj and Mahaiwon
Present Lab members:
- Ms Mahaiwon Shadang, PhD student, SRF-CSIR
Mahaiwon is investigating the molecular associations and clinical significance of the R2TP complex in cervical cancer. She joined the lab in August 2017 and completed her M.Sc. Medical Biochemistry in AIIMS, New Delhi in 2019 with a thesis that analyses the expression of the R2TP complex in Diffuse Large B Cell Lymphoma. She qualified for the CSIR NET JRF in 2017.
- Mr Dhiraj Kumar Singh, PhD Student, SRF-CSIR
Dhiraj started work at AIIMS as JRF in 2018 and enrolled as a PhD student in 2019. He studies the role of PIH1D1 (a subunit of the R2TP complex) in various phases of the cell cycle. He has completed his M.Sc. Bioinformatics from Jamia Millia Islamia University. He also qualified for the CSIR JRF in 2017 with AIR-63.
- Mr Pankaj Keshari, SRF
Pankaj’s work studies the trans-differentiation of inner ear supporting cells. This will provide insight into the development and function of supporting cells, leading to a better understanding of the biological roles these cells play.
- Hema Yadav, PhD student, JRF-DBT
Hema studies the role of the R2TP complex in the etiology of thyroid cancer. She completed her M.Sc. Medical Biochemistry in AIIMS, New Delhi in 2021. Her Master's thesis explored the role of B cells in a spectrum of Tuberculosis. She has qualified CSIR JRF and DBT JRF.
- Ayesha Rahman, PhD student, JRF-ICMR
Ayesha joined in October 2022 and works on “Effect of genetic manipulation in mammalian inner ear cells”. She completed her M.Sc. Biosciences from Jamia Millia Islamia University. She qualified ICMR JRF(AIR-51).
- Sipriha Saxena (MD Biochemistry) She joined in February 2024
Key publications:
- Hossain, M.M., Khalid, A., Akhter, Z. et al. Discovery of a novel and highly selective JAK3 inhibitor as a potent hair growth promoter. J Transl Med 22, 370 (2024). https://doi.org/10.1186/s12967-024-05144-4.
- yadav VS, Bhatia A, Yadav R, Makker K, Singh DK, Mir RA. Effect of initial periodontal therapy on metallothionein levels in smokers and non-smokers with periodontitis. Odontology. 2024 Apr 8. doi: 10.1007/s10266-024-00937-x
- Boruah Monikongkona, Gaddam Pranitha, Agarwal Shipra, Mir Riyaz Ahmad, Gupta Ranjan, Sharma Mehar C, Deo Suryanarayana V.S, Nilima Nilima. PD-L1 expression in rare and aggressive thyroid cancers: A preliminary investigation for a role of immunotherapy. Journal of Cancer Research and Therapeutics 2023 19(2):312-320,
- Morankar Rahul, Nitesh Tewari, Vijay Mathur, Atif Mohammad, Kalpana Bansal, Sandeep Agrawal, Riyaz Mir. In-vitro Evaluation for Effects of Intracanal Medicaments on Viability, Proliferation, and Differentiation of Stem Cells From Apical Papilla–A Systematic Review. European Endodontic Journal 2022 (7) 3:167-168
- Mishra N, Kumar S, Singh S, Bansal T, Jain N, Saluja S, Kumar R, Bhattacharyya S, Palanichamy JK, Mir RA, Sinha S, Luthra K. Cross-neutralization of SARS-CoV-2 by HIV-1 specific broadly neutralizing antibodies and polyclonal plasma. PLoS Pathog. 2021 Sep 24;17(9):e1009958. doi: 10.1371/journal.ppat.1009958. PMID: 34559854; PMCID: PMC8494312.
- Lone M, Shadang M, Akhter Q, Kumar M, Mallick S, Gogia A, Nilima N, Chauhan SS, Mir RA. The Expression of the RUVBL1 Component of the R2TP Complex Correlates with Poor Prognosis in DLBCL. Pathobiology. 2022;89(3):146-156. doi: 10.1159/000520723. Epub 2022 Jan 25. PMID: 35078195.
- Yadav VS, Mir RA, Bhatia A, Yadav R, Shadang M, Chauhan SS, Dhingra K, Kharbanda OP, Yadav R, Garg R. Metallothionein levels in gingival crevicular fluid, saliva, and serum of smokers and non-smokers with chronic periodontitis. J Periodontol. 2021 Sep;92(9):1329-1338. doi: 10.1002/JPER.20-0314. Epub 2020 Nov 9. PMID: 33107036.
- Sharma R, Kumar V, Logani A, Chawla A, Mir RA, Sharma S, Kalaivani M. Association between the concentration of active MMP-9 in pulpal blood and pulpotomy outcome in permanent mature teeth with irreversible pulpitis - a preliminary study. Int Endod J. 2021 Apr;54(4):479-489. doi: 10.1111/iej.13437. Epub 2020 Dec 13. PMID: 33128238.
- Olou AA, Sarkar A, Bele A, Gurumurthy CB, Mir RA, Ammons SA, Mirza S, Saleem I, Urano F, Band H, Band V. Mammalian ECD protein is a novel negative regulator of the PERK arm of unfolded protein response. Mol Cell Biol. 2017 28;37(18). pii e00030-17
- Dar MS, Singh P, Mir RA, Dar MJ. Βeta-catenin N-terminal domain: An enigmatic region prone to cancer-causing mutations. Mutat Res Rev Mutat Res. 2017 Jul;773:122-133. doi: 10.1016/j.mrrev.2017.06.001. Epub 2017 Jun 12. PMID: 28927523.
- Mir RA, Lovelace J, Schafer NP, Simone PD, Kellezi A, Kolar C, Spagnol G, Sorgen PL, Band H, Band V, Borgstahl GEO. Biophysical characterization and modeling of human Ecdysoneless (ECD) protein supports a scaffolding function. AIMS Biophys. 2016;3(1):195-208. doi: 10.3934/biophy.2016.1.195. Epub 2016 Mar 9. PMID: 28492064; PMCID: PMC5421643.
- Mir RA, Bele A, Mirza S, Srivastava S, Olou AA, Ammons SA, Kim JH, Gurumurthy CB, Qiu F, Band H, Band V. A Novel Interaction of Ecdysoneless (ECD) Protein with R2TP Complex Component RUVBL1 Is Required for the Functional Role of ECD in Cell Cycle Progression. Mol Cell Biol. 2015 Dec 28;36(6):886-99. doi: 10.1128/MCB.00594-15. PMID: 26711270; PMCID: PMC4810467.
- Bele A, Mirza S, Zhang Y, Mir RA, Lin S, Kim JH, Gurumurthy CB, West W, Qiu F, Band H, Band V. The cell cycle regulator ecdysoneless cooperates with H-Ras to promote oncogenic transformation of human mammary epithelial cells. Cell Cycle. 2015;14(7):990-1000. doi: 10.1080/15384101.2015.1006982. PMID: 25616580; PMCID: PMC4614725.
- Chaturvedi NK, Mir RA, Band V, Joshi SS, Guda C. Experimental validation of predicted subcellular localizations of human proteins. BMC Res Notes. 2014 Dec 15;7:912. doi: 10.1186/1756-0500-7-912. PMID: 25510246; PMCID: PMC4301851.
- Kumar R, Tripathi V, Ahmad M, Nath N, Mir RA, Chauhan SS, Luthra K. CXCR7 mediated Giα independent activation of ERK and Akt promotes cell survival and chemotaxis in T cells. Cell Immunol. 2012;272(2):230-41. doi: 10.1016/j.cellimm.2011.09.015. Epub 2011 Oct 20. Erratum in: Cell Immunol. 2014 Aug;290(2):251. PMID: 22070874.
- Mir RA, Chauhan SS. Down-regulation of a matrix degrading cysteine protease cathepsin L, by acetaldehyde: role of C/EBPα. PLoS One. 2011;6(6):e20768. doi: 10.1371/journal.pone.0020768. Epub 2011 Jun 8. PMID: 21687683; PMCID: PMC3110794.
- Mittal S, Mir RA, Chauhan SS. Post-transcriptional regulation of human cathepsin L expression. Biol Chem. 2011 May;392(5):405-13. doi: 10.1515/BC.2011.039. Epub 2011 Mar 14. PMID: 21395501.
- Katara R*, Mir RA*, Shukla AA, Tiwari A, Singh N, Chauhan SS. Wild-type p53-dependent transcriptional upregulation of cathepsin L expression is mediated by C/EBPα in human glioblastoma cells. Biol Chem. 2010 Sep;391(9):1031-40. doi: 10.1515/BC.2010.103. PMID: 20536385. *Equal authorship
Dr.
Pragyan Acharya
Male
Affiliation
Assistant Professor
Department of
Biochemistry
Contact
Phone :
91-011-26546431
Laboratory of Liver Disease Signaling and Immunology (LLDSI)
About the Principal Investigator:
- Name of Faculty MemberPragyanAcharya, Ph.D.
- Designation Assistant Professor
- Address Room No. 3002, 3rd floor Teaching Block, Department of Biochemistry, AIIMS, New Delhi-29.
- Official Phone +91-011-26546431
- Email id pragyan.acharyaATaiims.edu
- Social media links
https://in.linkedin.com/in/pragyan-acharya-40599b16
@Acharya3Dr
Notable Awards and Society Memberships
GRANTS AND FELLOWSHIPS:
- SERB POWER Grant 2022 towards in-depth characterization of neutrophil phenotypes in Acute-on-chronic liver failure (ACLF).
- AYUSH Extramural Grant 2021 towards identification and characterization of phytomedicine preparations from Indian traditional medicines.
- 2016- DBT BioCARE Award
- 2016-DST Early Career Award
- Grant for 2017 EMBO Global Exchange Lecture Course entitled Malaria Genomics and Public Health.
AWARDS AND HONORS:
- Editorial Board Member, PeerJ
- Indian National Association for the Study of the Liver (INASL) 2022 Plenary Session Award for our work on biomarkers of acute kidney injury (AKI) in acute-on-chronic liver failure (ACLF)
- Indian National Association for the Study of the Liver (INASL) 2021 Plenary Session Award for our work on neutrophil phenotypes in acute-on-chronic Liver Failure (ACLF).
- Fellows Award for Research Excellence 2015- sponsored by the NIH Scientific Directors, the Office of Intramural Training & Education and FelCom/NIH.
- Fellowship in the Khorana Nirenberg Scholars Program (US-India Career Transition Award- sponsored by DBT, India and NIH, USA) 2011
- Ranbaxy Science Scholar 2010
SOCIETY MEMBERSHIPS:
- Indian Society of Translational Research
- Proteomics Society of India
- Human Proteome Organization
- Indian Immunology Society
- Indian National Association for the Study of the Liver
LAB MEMBERS:
Front : Dr. Pragyan Acharya
Back row (L to R): Nidhi Gauniyal, Shalini Sharma, Swati Srijaya Samantaray, Ditam Chakraborty, Rohini Saha, Aditya Roshan, Souvik Roy
WHAT THEY DO:
Rohini Saha- Studies neutrophil heterogeneity and its role in the Pathogenesis of Acute-on-Chronic Liver failure (ACLF). Rohini has also led some of the biomarker discovery projects in the lab.
Shalini Sharma- Studies the relationship between reactive oxygen species generation and organ dysfunctions
Ditam Chakaraborty- Studies the effect of ayurvedic formulation on the SARS-COV2 main protease in various cellular systems
Swati Srijaya Samantaray- Is involved in omics- driven biomarker discovery in organ dysfunctions and validation by various methods.
Nidhi Gauniyal- Is involved in establishing novel diagnostic methodologies for inherited liver disorders.
Aditya Roshan and Souvik Roy- are the newest additions to the lab and will be involved in studying neutrophil transmigration and NETosis respectively.
# As Corresponding author; * As First Author
- Saha R, Pradhan SS, Shalimar, Das P, Mishra P, Singh R, Sivaramakrishnan V, Acharya P#. Inflammatory signature in acute-on-chronic liver failure includes increased expression of granulocyte genes ELANE, MPO and CD177. Sci Rep. 2021. Sep 22;11(1):18849. doi: 10.1038/s41598-021-98086-6.
- Acharya P*#, Chouhan K, Weiskirchen S and Weiskirchen R# Cellular Mechanisms of Liver Fibrosis.Front. Pharmacol. 202112:671640. doi: 10.3389/fphar.2021.671640
- Mandage R, Pramanik A, Kaur C, Sinha V, Kodan P, Singh A, Saha A, Pandey S, Wig N, Pandey RM, Soneja S, Acharya P#. Association of Dengue and Leptospira Co-infections with Malaria Severity. Emerging Infectious Diseases 2020. 26; 8; https://doi.org/10.3201/eid2608.191214
- Kaur, C, Pramanik, A, Kumari, K, Mandage R, Dinda A.K, Sankar, J, Bagga A, Agarwal, S.K., Sinha A., Singh G, Acharya P#. Renal detection of Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi in malaria associated acute kidney injury: a retrospective case–control study.BMC Research Notes 2020 13, 37; doi:10.1186/s13104-020-4900-1
- Singh A, Pramanik A, Acharya P, Makharia GK. Non-Invasive Biomarkers for Celiac Disease. Journal of Clinical Medicine 2019Jun 21;8(6). pii: E885; doi:10.3390/jcm8060885
- Acharya P*, Kutum R, Pandey R, Mishra A, Saha R, Munjal A, Ahuja V, Mukerji M, Makharia GK. First Degree Relatives of Patients with Celiac Disease Harbour an Intestinal Transcriptomic Signature that Might Protect them from Enterocyte Damage. Clinical and Translational Gastroenterology 2018 Oct 8;9(10):195. doi: 10.1038/s41424-018-0059-7
- Alampalli S, Grover M, Chandran S, Tatu U, Acharya P#. Proteome and Structural Organization of the Knob Complex on the Surface of the Plasmodium Infected Red Blood Cell. Proteomics- Clinical Applications 2017 Oct 5. doi: 10.1002/prca.201600177
- Acharya P#, Garg M, Kumar P, Munjal A, Raja KD. Host-Parasite Interactions in Human Malaria: Clinical Implications of Basic Research. Frontiers in Microbiology 2017 May 18;8:889. doi: 10.3389/fmicb.2017.00889. eCollection. Review.
- Acharya P*, Chaubey S, Grover M, Tatu U. An exported heat shock protein 40 associates with pathogenesis-related knobs in Plasmodium falciparum infectederythrocytes. PLoS One 2012;7(9):e44605.
- Acharya P*, Pallavi R*, Chandran S, Dandavate V, Sayeed S K, Rochani A, Acharya J, Middha S, Kochar S, Kochar D, Ghosh S K, Tatu U. PLoS One2011; 6(10):e26623. *These authors have contributed equally.
- Pallavi R, Acharya P*, Chandran S, Daily JP, Tatu U. Chaperone expression profiles correlate with distinct physiological states of Plasmodium falciparum in malaria patients. Malaria Journal 2010 Aug 19;9: 236.
- Pesce E R, Acharya P, Tatu U, Nicoll W S, Shonhai A, Hoppe H C, Blatch G L. International Journal of Biochemistry and Cell Biology2008; 40(12): 2914-26.
- Acharya P*, Kumar R, Tatu U. Chaperoning a cellular upheaval in malaria: heat shock proteins in Plasmodium falciparum. Molecular and Biochemical Parasitology 2007 Jun; 153(2):85-94. Epub 2007 Jan 17. Review.
Book Chapters
- Duffy P E, Acharya P and Oleinikov A. Cytoadherence of the Malaria Parasite. Encyclopedia of Malaria. Springer Publications. 2015.
- Acharya P*,Grover M and Tatu U. Systems Biology of Malaria. Encyclopedia of Systems Biology. Springer Publications. 2013.
