Scientist-I

Department of Biophysics, Near Lecture Theater-2, PC Block, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029

Phone (office): +91-11-26594259, Ext: 4259

Email: uddipan.das@aiims.edu

• 2016 - present: Scientist-I (Department of Biophysics, All India Institute of Medical Sciences, New Delhi)
• 2014-2016: Senior Resident/Demonstrator (Department of Biophysics, All India Institute of Medical Sciences, New Delhi)

• Visiting scientist at the University of Stanford, Cryo-EM center, California 2022-2023.
• SERB international research experience award (Government of India) 2022.
• Visiting scholar at European Molecular biology Laboratory, Hamburg, Germany, 2013.
• European Molecular Biology Organization (EMBO) Fellowship 2013.
• Indian Council of Medical Research Junior research fellowship 2009.
• Department of Biotechnology Junior research fellowship 2009.
• Graduate Aptitude Rest in Engineering (Life Sciences), 2009
• Centre of Scientific and Industrial Research NET 2009.

Google Scholar Link: https://scholar.google.com/citations?user=_YQkkBcAAAAJ&hl=en

• Singh M, Haque MA, Tikhomirov A, Shchekotikhin, A, Das U, Kaur, P (2022). Computational and biophysical characterization of heterocyclic derivatives of anthraquinone against Human Aurora Kinase A. ACS Omega (accepted)
• Sharma P, Kumar M, Tripathi MK, Gupta D, Vishwakarma P, Das U & Kaur P (2022) Genomic and structural mechanistic insight to reveal the differential infectivity of omicron and other variants of concern. Comput Biol Med 150, 106129.
• Sharma D, Singh M, Kaur P & Das U* (2022) Structural analysis of LpqY, a substrate-binding protein from the SugABC transporter of Mycobacterium tuberculosis , provides insights into its trehalose specificity. Acta Crystallogr Sect D Struct Biol 78, 835–845.
• Gupta D, Kumar M, Singh M, Salman M, Das U & Kaur P (2022) Identification of polypharmacological anticancerous molecules against Aurora kinase family of proteins. J Cell Biochem 123, 719–735.
• Singh M, Malhotra L, Haque MA, Kumar M, Tikhomirov A, Litvinova V, Korolev AM, Ethayathulla AS, Das U, Shchekotikhin AE & Kaur P (2021) Heteroarene-fused anthraquinone derivatives as potential modulators for human aurora kinase B. Biochimie 182, 152–165.
• Sabharwal N, Varshney K, Rath PP, Gourinath S & Das U* (2020) Biochemical and biophysical characterization of nucleotide binding domain of Trehalose transporter from Mycobacterium tuberculosis. Int J Biol Macromol 152, 109–116.
• Das U*, Singh E, Dharavath S, Tiruttani Subhramanyam UK, Pal RK, Vijayan R, Menon S, Kumar S, Gourinath S & Srinivasan A (2019) Structural insights into the substrate binding mechanism of novel ArgA from Mycobacterium tuberculosis. Int J Biol Macromol 125, 970–978.
• Gupta AK, Pokhriyal R, Das U, Khan MI, Kumar DR, Gupta R, Chadda RK, Ramachandran R, Goyal V, Tripathi M & Hariprasad G (2019) Evaluation of α-synuclein and apolipoprotein e as potential biomarkers in cerebrospinal fluid to monitor pharmacotherapeutic efficacy in dopamine dictated disease states of parkinson’s diseaseand schizophrenia. Neuropsychiatr Dis Treat 15, 2073–2085.
• Das U, Pogenberg V, Subhramanyam UKT, Wilmanns M, Gourinath S & Srinivasan A (2014) Crystal structure of the VapBc-15 complex from mycobacterium tuberculosis reveals a two-metal ion dependent pin-domain ribonuclease and a variable mode of toxin-antitoxin assembly. J Struct Biol 188, 249–258.
• Das U, Kumar N, Gourinath S & Srinivasan A (2013) Preliminary crystallographic analysis of recombinant VapBC-15 toxin-antitoxin complex from Mycobacterium tuberculosis. Acta Crystallogr Sect F Struct Biol Cryst Commun 69, 1242–1245.