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Funded projects

Ongoing

S. No.Title of the projectName of Principal InvestigatorFunded by (Name of funding agency)Duration (years)Start year – End yearTotal funds sanctioned (Rs)
1Centre for Medical Innovation and EnterpreunershipAlok Thakar(AIIMS BioNEST)42020 - Ongoing4.75 crore
2A study on frailty, cognitive dysfunction and associated comorbidities with Hearing loss in Geriatric populationKapil SikkaICMR32024-202730.9 Lakhs
3Intraglandular Botulinum Toxin BoNT Injection for Postoperative Head and Neck Fistula Healing- A Pilot StudySmriti PandaIntramural early career grant22024-20265.85 Lakhs
4Prevention of Radiotherapy Induced Xerostomia by intraductal administration of N- Acetyl Cysteine in patients with Oropharyngeal malignancies: A Randomized Clinical TrialArvind Kumar KairoICMR42020-202436 Lakhs
5Local application of specific Unani drug for medical management of oral submucosal fibrosis (OSF) a randomized clinical control trialArvind Kumar KairoCCRUM22023-2435 Lakhs
6Phased pilot study to assess the baseline of serum level of Prestin in healthy individuals and in patients of definite Meniere’s Disease as a biomarker of cochlear outer hair cell functional statusDr Prem SagarAIIMS  5 Lakhs
7To evaluate nasal eosinophilic miRNAs as potentially diagnostic, prognostic and predictive biomarkers in allergic rhinitisDr Shuchita SinghAIIMS22022-245 Lakhs
8Transorbital approach to infratemporal Fossa - A cadaveric exploratory StudyDr Anup SinghAIIMS1 yearJan 20245 Lakhs
9Exome sequencing and molecular characterization in juvenile nasopharyngeal angiofibroma (COLLOBRATIVE PROJECT)HITESH VERMA/ DR BHUPINDER VERMAAIIMS22021-2320 Lakhs
10Development of single-cell derived clonal spheroids as a tool for drug discovery in cancer research with focus on Head and Neck CancerDR R.P.SINGH/ DR HITESH VERMADST42019-233 Crores
11Prospective study to evaluate the role of Systemic Bevacizumab therapy in patients with aggressive and complex laryngotracheal and pulmonary recurrent respiratory papillomatosis.Dr Rajeev KumarAIIMS Intramural Collaborative Research Project 2021-2320 Lakhs
12Study to determine the role of mTOR pathway in the pathogenesis of juvenile nasopharyngeal angiofibromaDr Rajeev KumarAIIMS Intramural Research Project12021-235 Lakhs
13Phased pilot study to assess baseline serum level of Prestin in healthy individuals and in patients of definite Meniere’s disease and ototoxicity as a biomarker of cochlear outer hair cell functional statusDr Prem SagarAIIMS, New Delhi Intramural project, A-83232020-234.5 Lakhs
14Device fabrication and clinical validation of a novel mechanical handheld suction device for tracheostomy tube cleaning: a pilot studyDr Prem Sagar (chief guide), Dr Ritu Dudi (PG thesis candidate)AIIMS, New Delhi22023-252 Lakhs
15Clinical validation of the effectiveness of automated speech therapy for stuttering delivered by digital meansShuchita Singh PachauryBIRAC2 years 3 months2020-2210 Lakhs
16To determine the efficacy of outpatient antimicrobial therapy (OPAT) with Liposomal amphotericin B in invasive sinonasal mucurmycosis, a randomised controlled trialDr. Poonam SagarResearch section, AIIMS, DelhiTwo years2024-202610 Lakhs

Completed :

S. No.Title of the projectName of Principal InvestigatorFunded by (Name of funding agency)Duration (years)Start year – End yearTotal funds sanctioned (Rs)
1Evaluation of factors impacting outcomes of cochlear implants in pediatric populationKapil SikkaICMR3.5 Years2029-202335.3 Lakhs
2Sound4All: Re-Engineering High end audiometric devices for robust and affordable audiological testing phase IIKapil SikkaIGSTC (Indo German Science and Technology Center)42019-202336 Lakhs
3An evaluation of HLA, phagocytic function and trace elements in cases of sinusitis, invasive fungal sinusitis and non-invasive fungal sinusitisHitesh VermaAIIMS42019-2310 Lakhs
4ACE-2 receptor expression in sino-nasal mucosa in patients with COVID 19 associated mucormycosisHitesh VermaAIIMS22021-233.7 Lakhs

Departmental projects (including thesis/dissertations) : Ongoing

S. No.Title of the project
1A pilot study to assess the effect of intraductal N acetyl cysteine on swallowing and voice outcomes of patients with oropharyngeal cancer undergoing radiotherapy
2To compare different Cochlear Implantation outcome scores with auditory cortical activity seen on functional near infrared spectroscopy in prelingual profound SNHL patients after Cochlear Implantation
3Analysis of voice outcomes after radiation or chemo radiation in carcinoma larynx and the effect of N acetyl cysteine on voice parameters
4Evaluation of respiratory and voice outcomes in patients with unilateral vocal cord palsy post injection laryngoplasty
5Exome sequencing and molecular characterization in juvenile nasopharyngeal angiofibroma
6A prospective study to measure the objective, subjective and aesthetic Outcomes in patients undergoing Septorhinoplasty
7A comparative study to evaluate functional outcomes following tongue reconstruction with radial artery forearm free flap and infrahyoid myocutaneous flap
8A single institutional prospective audit of type-1 tympanoplasty and evaluation of factors affecting the outcome.
9to compare post cochlear implant outcome in candidates with and without residual hearing (RH)
10Descriptive study of the anatomical variations of the superficial temporal artery and the posterior auricular artery in the patients with unilateral microtia and its implications on the surgical outcomes in auricular reconstruction surgery
11To evaluate prospective auditory cortical activity changes on functional near infrared spectroscopy in prelingual profound snhl patients undergoing cochlear implantation
12Serum prestin and otolin-1 as markers of cisplatin-induced ototoxicity in cervical cancer patientsThesis
13Role of Adjuvant Therapy in Early-Stage Oral Cavity Squamous Cell Carcinoma: An Ambispective Analysis
14Ambispective study to assess Universal Newborn Hearing Screening Program
15Comparative evaluation of CAD- CAM planning versus traditional free fibula planning in surgical outcomes in mandibular reconstruction-A prospective study
16Correlation of Depth Of Invasion with Lymph node Metastasis in Laryngeal and Hypopharyngeal carcinoma
17A prospective study to evaluate role of various frailty screening instruments in predicting surgical complications in geriatric head neck cancer patients.
18Comparative study evaluating Ex-Vivo US aided deep margin assessment with fresh frozen section analysis in T1-T3 tongue carcinoma: Feasibility study
19Ambispective study to assess various primary tumour and ipsilateral nodal factors associated with contralateral nodal metastasis in patients with OCSCC
20Study evaluating the effectiveness of Barbed suture versus Vicryl suture for pharyngeal closure after total laryngectomy in PCF reduction
21Prospective analysis of predictive factors for tracheal stomal stenosis after total laryngectomy for laryngeal and hypopharyngeal malignancies(2021 -2023, Non funded study)
22Role of ultrasound in predicting the depth of tumour invasion and lymph node metastasis in early tongue carcinoma.(2017-till date, Non-Funded Study)
23Evaluation of short term and long-term effects of cochlear implantation on vestibular function
24A prospective cohort study to evaluate the feasibility and accuracy of fetal vibroacoustic stimulation as a prenatal hearing screening tool
25Device fabrication and clinical validation of a novel mechanical handheld suction device for tracheostomy tube cleaning: a pilot study
26Short & Long term effects on vestibular apparatus of cochlear implant
27A Prospective study to measure the objective, subjective and aesthetic outcomes in patient undergoing Septorhinoplasty
27Prospective study to correlate rhinomanometry in DNS patients with endoscopy, NOSE score and NCCT PNS study
28A Randomized Control Trial to compare the outcomes of endoscopic and microscopic stapes surgery
29Prospective study to evaluate the efficacy of PNN as treatment modality in patient with PAR along with medical management
30To evaluate poor prognosis factors in laryngotracheal stenosis: An ambispective study
31Impact of NACT on surgical decision and perioperative outcome in patient with very advanced buccal cancer
32A randomised control trial on the effectiveness of anti fungal and stetoid nasal douching in allergic fungal rhinosinusitis: a clinical, radiological and biochemical corelation
33Descriptive study of the anatomical variations of the superficial temporal artery and the posterior auricular artery in the patients with unilateral microtia and its implications on the surgical outcomes in auricular reconstruction surgery
34Prospective audit of tympanoplasty and evaluation of factors affecting the outcome
35To assess the outcomes of lateral skull base lesions who have been surgically operated with special reference to quality of life
36Prospective assessment of auditory and cognitive performance in children undergoing ear surgeries: A comparative study
37Comparative analysis of qPCR, mRNA ISH and p16 IHC for detection of high risk HPV on fine needle aspirates and core needle biopsies in patients with metastatic squamous cell carcinoma in cervical lymph nodes
38Role of preoperative nutritional intervention in improving surgical outcome of patients with oral squamous cell carcinoma
39Effect of intranasal corticosteroids and antihistaminics v/s omalizumab on adenoid hypertrophy
40Effect of Palatal Morphology on Eustachian Tube Function in Children with Adenoid Hypertrophy: an Observation Study
41Assessment of pre-cervical (perimarginal and lingual) lymph nodes as first echelon for squamous cell carcinoma of oral cavity
42Adversity and QOL Post Treatment of Laryngeal and Hypopharyngeal Cancer and Impact of Novel AIMS-IIT-TEP in its Mitigation.
43Evaluating the effectiveness of Barbed suture versus Vicryl for pharyngeal closure after total laryngectomy in PCF reduction: A Randomised controlled study
44A Study analysing "Back to Normalcy" in Oral Cavity Cancer Survivors
45A prospective study to evaluate the role of various frailty screening instruments in predicting surgical complications in geriatric head neck cancer patients.
46Sentinel lymph node detection in oral squamous cell carcinoma with negative neck: comparison between [99mTc] Sulphur colloid AND [99mTc] DTPA ANTICytokeratin- Collagenous Nanoparticle (DC-Col NP)

Completed :

S.No.Title of the project
1A Prospective Study to evaluate the impact of Oral Sub mucous Fibrosis (OSMF) on occult and overt lymph nodal metastases in Gingivo-buccal complex carcinomas (GBCC) (T1-T4a) of Oral cavity
2A prospective study to determine early predictive factors of hypocalcemia in patients undergoing total or completion thyroidectomy
3Prospective pilot study to assess the effectiveness of novel Forehead Knuckle Tapping method in localisation of better or worse hearing ear as compared to conventional tuning fork testing
4A prospective pilot study to evaluate the effect of Supraglottoplasty on Tracheomalacia in pediatric patients with Congenital Laryngotracheomalacia
5An ambispective cohort control study to evaluate the incidence of SARS CoV-2 infection in post Adenoidectomy/Adenotonsillectomy patients
6Comparison Of Suction Verses Microdissection Method For Harvesting Supporting Cell From Inner Ear
7Observational study to correlate site of obstruction in OSA with eustachian tube dysfunction and reflux disorders
8Ambispective study to evaluate the utility of Supraclavicular artery island flap [SCAIF] reconstruction in Head and Neck Cancers
9A cohort study on determining the effect of preoperative residual hearing on post cochlear implant outcome

Collaborative projects : Ongoing

S. No.Title of the projectCollaborating department/institution
1To evaluate the role of Kit-based Loop-Mediated Isothermal Amplification (TB-LAMP) assay in the diagnosis of Extra-pulmonary tuberculosis (EPTB)Medicine Department
2Analysis of circulating DNA for BRAF (T 1799A) mutation as a futuristic non-invasive tool for diagnosis, prognostication, targeted therapy and folloW-up of papillary thyroid cancerPathology
3Phase IIb/III Study to determine efficacy of curcumin and Metformin to reduce the incidence of Second Primary tumors of Aero-digestive tract in patients with history of head and neck squamous cell carcinomaNational Cancer Grid
4Clinical validation of the effectiveness of automated speech therapy for stuttering delivered by digital meansBIRAC
5Effect of Cochlear implantation on middle ear and saccular functionCollabrative project with AIISH, Mysuru
6Molecular characterization of olfactory neuroblastomas for classification into prognostically and therapeutically relevant subgroups.Dr. Aanchal Kakkar ( Pathology- PI).
7Evaluation of Machine Learning Techniques including Deep Learning for the Identification of Malignancy in Tissue Samples.AIIMS- IIT Delhi Joint Collaborative Funding 019-2021, Dr. Aanchal Kakkar ( Pathology - PI).
8Inter- institutional program for maternal neonatal and infant science : A translational approach- interdisciplinary group for advanced research on birth outcomeDBT India initiative ( GARBH- Ini-Phase II)
9A study on the effect of genetic manipulation on mammalian inner ear cellsDept of Biochemistry
10Exome sequencing and molecular characterization in juvenile nasopharyngeal angiofibromaBiotechnology/ AIIMS
11Evaluation of specific molecular alterations and tumor immune microenvironment for detection of clinically actionable targets in high grade salivary gland carcinomasICMR Funded, Department of Pathology
12The SWOAR trial: A phase III trial evaluating dysphagia-aspiration related structures & submandibular gland sparing Intensity modulated radiotherapy (SWOAR-IMRT) versus standard IMRT in Head and neck squamous cell carcinomaDepartment of Radiotherapy
13The tumour immune microenvironment of follicular cell -derived thyroid carcinomas across different grades utilizing gene expression and spatial proteomic profilingDepartment of Pathology
14Role of celecoxib in reducing cognitive impairment in patients receiving definitive chemoradiation for head and neck carcinoma: A phase II randomized placebo controlled trialDepartment of Medical Oncology
15Potentially malignant lesion atlas project: Validating the efficacy of a novel, Point-of -care diagnostics and developing an integrated multidimensional, prognostic nomogramICMR funded, Department of Preventive Oncology, NCI AIIMS
16Comparative analysis of qPCR, mRNA ISH and p16 IHC for detection of high risk HPV on fine needle aspirates and core needle biopsies in patients with metastatic squamous cell carcinoma in cervical lymph nodesCollaborative Intramural, AIIMS
17A Phase III , Randomized Controlled Study of Utility of Pectoralis Major Myofascial Flap in Reducing Pharyngocutaneous Fistula Rates After Salvage Total Laryngectomy.TMH
18A randomised, sham controlled, double blind study to evaluate the efficacy of and safety of intra-thecal OAV101 in patients with later onset type-2 spinal muscular atrophy who are ≥ 2 to < 18 years of age, treatment naive, sitting, and never ambulatory.A phase 3 Clinical trial (STEER) by Novartis Pharmaceuticals.ClinicalTrials.gov Identifier:NCT05089656.
19Prevalence and pattern of traumatic dental injury in children and adolescents with severe to profound hearing impairment reporting to a tertiary care centre in North IndiaPediatric Dentistry, CDER, AIIMS, New Delhi
20Comparison of pulsed radio-frequency versusconventionalradio-frequency in secondary glossopharyngeal neuralgia: a randomised controlled trialDepartment of Anaesthesiology, AIIMS, New Delhi
21Perioperative anaesthetic management of paediatric congenital laryngomalacia- A retrospective studyDepartment of Anaesthesiology, AIIMS, New Delhi
22A Phase II trial of Pentoxiphylline and alpha tocopherol (PAT) in prevention of radiation induced dysphagia in head and neck squamous cell carcinomaRadio-therapy
23A Phase III prospective randomised trial comparing dysphagia-aspiration related structures & submandibular gland sparing Intensity modulated radiotherapy (SWOAR-IMRT) versus standard IMRT (s-IMRT) paring in locally advanced oropharyngeal and laryngeal carcinomasRadio-therapy
24Ultrasonographic assessment of tonsillar volume in children undergoing tonsillectomy : a predictor of post operative morbidityAnaesthesiology

Complete

S. No.Title of the projectCollaborating department/institution
1To Understand the Biochemical and Molecular Basis of Mucormycosis in COVID-19 PatientsDept of Biotechnology
2Evaluation of genetic profile of olfactory neuroblastomaDepartment of Pathology
3Comparison between kit based and in-house preparation of Tc -99m UbiquicidinDepartment of Nuclear Medicine
4Utility of 99m Tc- Ubiquicidin scintigraphy in diagnosis of sinonasal mucormycosisDepartment of Nuclear Medicine
5Utility of Ga - 68 - NOTA- UBI in infectious and non- infectious lesionsDepartment of Nuclear Medicine
6A phase II study of EMF (Erlotinib+ Methotrexate+ Celecoxib) in platinum refractory recurrent /metastatic head neck squamous cell carcinomaDepartment of Medical Oncology
7Assessment of Oral Microbiome and its significance in upper aerodigestive tract cancersDepartment of Medical Oncology
8A cohort study to assess the feasibility of WHO ICOPE approach in tertiary health centresDepartment of Geriatrics, AIIMS, New Delhi
9A longitudinal Survey to assess Patient Satisfaction for Nurse Initiated Follow Up Tele-Consultation among patients discharged from a selected tertiary care hospitalNursing department
10An OMR sheet based feed-back survey on in-patient satisfaction regarding various hospital services in a selected tertiary care hospitalNursing department