Tony George Jacob

Affiliation

Professor

Department of

Anatomy

Contact

Email :

Phone :

Additional Responsibility

Office Address

General OPD

Special Clinic

Surgery Days

Speciality of work

Areas of teaching

Tony joined AIIMS as faculty in 2014. He is continuing his work on the pathogenesis of pancreatitis. Now, he and his team have also established two surgical models of acute pancreatitis in rats at the Institute, which also measures organ dysfunction. He is also working on two models of chronic pancreatitis. His work includes the role of autophagy, cell death and inflammation in the pathogenesis of acute and chronic pancreatitis. He also studies the development and effect of aging on the various components of the human auditory system.

He is interested in teaching various aspects of anatomy and has a special interest in history, especially that of medical education. He is also a resource person for Mentoring, Interpersonal Communication Skills and Personality Development in the Health Sector and also for medical research, writing a manuscript and the process of reviewing and editing.

Chapter in books:

Changing populations of neurons and glia in human cochlear nucleus with aging- Chapter 12
Morphology of the human pancreas during development and aging- Chapter 4 P.C Rath, R. Sharma, S. Prasad Eds: Topics in Biomedical Gerontology.
Parija SC, Adkoli BV Eds: Effective Medical Communication- the ABCD of it. Chapter: Jacob TG, Sahni P: Publishing effectively and ethically. Springer Singapore. 2020. pp 123-130. doi: 10.1007/978-981-15-3409-6.

Indrapal, Paltati CRB, Saini S, Kaur C, Kumar P, Bhardwaj DN, Jacob TG, Roy TS. Morphological and neurochemical changes in GABAergic neurons of the aging human inferior colliculus. Hearing Research. 2019. March 2019. Hearing Research 377. DOI:10.1016/j.heares.2019.02.005
Poorna Pillutla SV, Kaur C, Roy TS, Jacob TG. Estimation of Volume of Stria Vascularis and the Length of Its Capillaries in the Human Cochlea. J Microsc Ultrastruct. 2019 Jul-Sep;7(3):117-123. doi: 10.4103/JMAU.JMAU_12_19. PMID:31548922
Saini S, Kaur C, Pal I, Kumar P, Jacob TG, Thakar A, Roy KK, Roy TS. Morphological development of the human cochlear nucleus. Hear Res. 2019 Oct; 382:107784. doi: 10.1016/j.heares.2019.107784. Epub 2019 Aug 20. PMID:31522073
Kaur C, Saini S, Pal I, Kumar P, Sati HC, Jacob TG, Bhardwaj DN, Roy TS. Age-related changes in the number of cresyl-violet-stained, parvalbumin and NMDAR 2B expressing neurons in the human spiral ganglion. Hearing Res. 2020. https://doi.org/10.1016/j.heares. 2020.107883
Kumar A, Faiq MA, Krishna H, Raj GV, Kishan V, Coffey JC, Jacob TG. Development of a Novel Technique to Dissect the Mesentery that Preserves Mesenteric Continuity and Enables Characterization of the Ex Vivo Mesentery. Front. Surg. 2020. doi: 10.3389/fsurg.2019.00080
Ahuja R, Sharma N, Vashisht P, Jacob TG, Narang R, Bhatnagar N. Biocompatibility Analysis of PLA based Candidate Materials for Cardiovascular Stents in a Rat Subcutaneous Implant Model. Acta Histochemica. 2020;122(7):151615. doi: 10.1016/j.acthis.2020.151615
Raghav R, Jain R, Jacob TG, Dhawan A, Roy TS. Co-administration of nalbuphine attenuates the morphine-induced anxiety and dopaminergic alterations in morphine-withdrawn rats. Psychopharmacology (Berl). 2021 Apr;238(4):1193-1211. doi: 10.1007/s00213-021-05765-3
Nag HL, Jain G, Vijayakumar V, Jacob TG, Sonai M, Lalwani S. Femoral Intercondylar Notch: Gross Anatomy and Histology of the Connective Tissue Lining of its Roof: A Pilot Study. Surg Rad Anat. 2021. doi.org/10.1007/s00276-021-02757-y.
Kumar P, Sharma S, Kaur C, Pal I, Bhardwaj DN, Vanamail P, Roy TS, Jacob TG. The ultrastructural study of human cochlear nerve at different ages. Hearing Research 2022. (in press). https://doi.org/10.1016/j.heares.2022.108443
M. Uppal, T.G. Jacob, H.N. Yadav, S.K. Datta, R. Yadav, S.J. Mahapatra, P. Garg, P. Sahni, Therapeutic Methylprednisolone and Infimab Decrease the Severity of Organ Dysfunction in Pancreatic Duct Ligation Model of Severe Acute Pancreatitis in Wistar Rats, HPB, Volume Supplement 3, 2021, Page S739, ISSN 1365-182X, https://doi.org/10.1016/j.hpb.2021.08.136.
Sharma MK, Priyam K, Kumar P, Garg PK, Roy TS, Jacob TG. Effect of calorie-restriction and rapamycin on autophagy and the severity of caerulein-induced experimental acute pancreatitis in mice. Front. Gastro (Therapy in Gastroenterology). 2022. Accepted for publication.