Dr.
Ajay Godwin Potnuri
Male
M.S (Pharm), Ph.D.
Affiliation
Scientist
Department of
Pharmacology
National Poisons Information Centre
Contact
Email :
dr[dot]ajaygodwin[dot]p[at]gmail[dot]com
Phone :
011-26593677
Office Address
4th Floor, Department of Pharmacology, Teaching Block, All India Institute of Medical Sciences (AIIMS), New Delhi 110029
Area of Interest:
Cardiovascular Pharmacology and toxicology with a special emphasis on hypertensive heart disease and vascular biology
Education:
- B.Pharmacy from Andhra University, Visakhapatnam
- M.S (Pharm) in Pharmacology and Toxicology from National Institute of Pharmaceutical Education and Research, Guwahati
- Ph.D in Biological Sciences from Sree Chitra Tirunal Institute for Medical Sciences and Technology,Thriuvananthapuram
- ICMR PDF from ICMR NARFBR, Turkapally, Shamirpet, Hyderabad
Research Interest/ area:
Cardiovascular Pharmacology and toxicology with a special emphasis on hypertensive heart disease and vascular biology
Past Position:
Assistant Research Officer (Pharmacology) at National Ayurveda Research Institute for Panchakarma, Cheruthuruthy, Thrissur, Kerala (Jan’ 2021 – Sep’ 2022)
Ongoing Projects:
- Evaluation of Guduchi Sattva for its anti-platelet and thrombolytic potential using in-vitro and in-vivo experimental models, funded by Indian Council for Medical Research. [Budget:15,90,000]
Completed Projects:
- Acute and 90 days Toxicity profiling of AYUSH 64, funded by Central Council for Research in Ayurvedic Sciences. [Budget:18,97,450]
- Understanding the role of FFAR2 In Modulating atherosclerosis in WNIN/Ob rat, funded by Indian Council for Medical Research. [Budget:21,60,000]
Selected Publications:
- Potnuri AG, Allakonda L, Appavoo A, Saheera S, Nair RR. Targeting histamine-2 receptor for prevention of cardiac remodeling in chronic pressure overload. Int J Card. 2016;202:831-833.
- Kondru SK, Potnuri AG, Allakonda L, Konduri P. Histamine 2 receptor antagonism elicits protection against doxorubicin-induced cardiotoxicity in rodent model. Molecular and Cellular Biochemistry. 2018;1-12.
- Sudam VS, Potnuri AG, Subhashini NJP. Syk–GTP RAC-1 mediated immune-stimulatory effect of Cuscuta epithymum, Ipomoea batata, and Euphorbia hirta plant extracts. Biomedicine & Pharmacotherapy. 2018;96:742-749.
- Saheera S, Potnuri AG, Nair RR. Modulation of cardiac stem cell characteristics by metoprolol in hypertensive heart disease. Hypertension Research. 2018 Feb 15. doi:10.1038/s41440-018-0015-7.
- Saheera S, Potnuri AG, Nair RR. Histamine-2 receptor antagonist Famotidine modulates cardiac stem cell characteristics in hypertensive heart disease. PeerJ. 2017 Oct 9;5:e3882. doi:10.7717/peerj.3882.
- Potnuri AG, Allakonda L, Lahkar M. Crocin attenuates cyclophosphamide-induced testicular toxicity by preserving glutathione redox system. Biomedicine & Pharmacotherapy. 2018;101:174-180.
- Potnuri AG, Allakonda L, Appavoo A, Saheera S, Nair RR. Association of histamine with hypertension-induced cardiac remodeling and reduction of hypertrophy with histamine-2 receptor antagonist famotidine in comparison with beta-blocker metoprolol. Hypertension Research. 2018.
- Saheera S, Potnuri AG, Nair RR. Protective effect of antioxidant Tempol on cardiac stem cells in chronic pressure overload hypertrophy. Life Sciences. 2019;222:88-93.
- Potnuri AG, Allakonda L, Saheera S. Involvement of histamine-2 receptor in Alpha-1 adrenoceptor-mediated cardiac hypertrophy and oxidative stress in H9c2 cardiomyoblasts. J Cardiovasc Transl Res. 2021 Feb;14(1):184-194.
- Allakonda L, Kakaraparthi A, Potnuri AG. Beta-1 adrenoceptor blockade promotes angiogenesis in hypertrophied myocardium of TAC rat. Clinical and Experimental Pharmacology and Physiology. 2021;48(1):121-128.
