Dr.
Ajay Godwin Potnuri
M.S (Pharm), Ph.D.
Affiliation
Scientist
Department of
Pharmacology
Contact
Email :
dr.ajaygodwin.p@gmail.com
Phone :
011-26593677
Additional Responsibility
Office Address
4th Floor, Department of Pharmacology, Teaching Block, All India Institute of Medical Sciences (AIIMS), New Delhi 110029
General OPD
Special Clinic
Surgery Days
Speciality of work
Areas of teaching
Areas of teaching
Area of Interest:
Cardiovascular Pharmacology and toxicology with a special emphasis on hypertensive heart disease and vascular biology
Education:
- B.Pharmacy from Andhra University, Visakhapatnam
- M.S (Pharm) in Pharmacology and Toxicology from National Institute of Pharmaceutical Education and Research, Guwahati
- Ph.D in Biological Sciences from Sree Chitra Tirunal Institute for Medical Sciences and Technology,Thriuvananthapuram
- ICMR PDF from ICMR NARFBR, Turkapally, Shamirpet, Hyderabad
Research Interest/ area:
Cardiovascular Pharmacology and toxicology with a special emphasis on hypertensive heart disease and vascular biology
Past Position:
Assistant Research Officer (Pharmacology) at National Ayurveda Research Institute for Panchakarma, Cheruthuruthy, Thrissur, Kerala (Jan’ 2021 – Sep’ 2022)
Ongoing Projects:
- Evaluation of Guduchi Sattva for its anti-platelet and thrombolytic potential using in-vitro and in-vivo experimental models, funded by Indian Council for Medical Research. [Budget:15,90,000]
Completed Projects:
- Acute and 90 days Toxicity profiling of AYUSH 64, funded by Central Council for Research in Ayurvedic Sciences. [Budget:18,97,450]
- Understanding the role of FFAR2 In Modulating atherosclerosis in WNIN/Ob rat, funded by Indian Council for Medical Research. [Budget:21,60,000]
Selected Publications:
- Potnuri AG, Allakonda L, Appavoo A, Saheera S, Nair RR. Targeting histamine-2 receptor for prevention of cardiac remodeling in chronic pressure overload. Int J Card. 2016;202:831-833.
- Kondru SK, Potnuri AG, Allakonda L, Konduri P. Histamine 2 receptor antagonism elicits protection against doxorubicin-induced cardiotoxicity in rodent model. Molecular and Cellular Biochemistry. 2018;1-12.
- Sudam VS, Potnuri AG, Subhashini NJP. Syk–GTP RAC-1 mediated immune-stimulatory effect of Cuscuta epithymum, Ipomoea batata, and Euphorbia hirta plant extracts. Biomedicine & Pharmacotherapy. 2018;96:742-749.
- Saheera S, Potnuri AG, Nair RR. Modulation of cardiac stem cell characteristics by metoprolol in hypertensive heart disease. Hypertension Research. 2018 Feb 15. doi:10.1038/s41440-018-0015-7.
- Saheera S, Potnuri AG, Nair RR. Histamine-2 receptor antagonist Famotidine modulates cardiac stem cell characteristics in hypertensive heart disease. PeerJ. 2017 Oct 9;5:e3882. doi:10.7717/peerj.3882.
- Potnuri AG, Allakonda L, Lahkar M. Crocin attenuates cyclophosphamide-induced testicular toxicity by preserving glutathione redox system. Biomedicine & Pharmacotherapy. 2018;101:174-180.
- Potnuri AG, Allakonda L, Appavoo A, Saheera S, Nair RR. Association of histamine with hypertension-induced cardiac remodeling and reduction of hypertrophy with histamine-2 receptor antagonist famotidine in comparison with beta-blocker metoprolol. Hypertension Research. 2018.
- Saheera S, Potnuri AG, Nair RR. Protective effect of antioxidant Tempol on cardiac stem cells in chronic pressure overload hypertrophy. Life Sciences. 2019;222:88-93.
- Potnuri AG, Allakonda L, Saheera S. Involvement of histamine-2 receptor in Alpha-1 adrenoceptor-mediated cardiac hypertrophy and oxidative stress in H9c2 cardiomyoblasts. J Cardiovasc Transl Res. 2021 Feb;14(1):184-194.
- Allakonda L, Kakaraparthi A, Potnuri AG. Beta-1 adrenoceptor blockade promotes angiogenesis in hypertrophied myocardium of TAC rat. Clinical and Experimental Pharmacology and Physiology. 2021;48(1):121-128.
