
Dr.
Tony George Jacob
Affiliation
Professor
Department of
Anatomy
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Tony joined AIIMS as faculty in 2014. He is continuing his work on the pathogenesis of pancreatitis. Now, he and his team have also established two surgical models of acute pancreatitis in rats at the Institute, which also measures organ dysfunction. He is also working on two models of chronic pancreatitis. His work includes the role of autophagy, cell death and inflammation in the pathogenesis of acute and chronic pancreatitis. He also studies the development and effect of aging on the various components of the human auditory system.
He is interested in teaching various aspects of anatomy and has a special interest in history, especially that of medical education. He is also a resource person for Mentoring, Interpersonal Communication Skills and Personality Development in the Health Sector and also for medical research, writing a manuscript and the process of reviewing and editing.
Chapter in books:
- Changing populations of neurons and glia in human cochlear nucleus with aging- Chapter 12
- Morphology of the human pancreas during development and aging- Chapter 4 P.C Rath, R. Sharma, S. Prasad Eds: Topics in Biomedical Gerontology.
- Parija SC, Adkoli BV Eds: Effective Medical Communication- the ABCD of it. Chapter: Jacob TG, Sahni P: Publishing effectively and ethically. Springer Singapore. 2020. pp 123-130. doi: 10.1007/978-981-15-3409-6.
- Indrapal, Paltati CRB, Saini S, Kaur C, Kumar P, Bhardwaj DN, Jacob TG, Roy TS. Morphological and neurochemical changes in GABAergic neurons of the aging human inferior colliculus. Hearing Research. 2019. March 2019. Hearing Research 377. DOI:10.1016/j.heares.2019.02.005
- Poorna Pillutla SV, Kaur C, Roy TS, Jacob TG. Estimation of Volume of Stria Vascularis and the Length of Its Capillaries in the Human Cochlea. J Microsc Ultrastruct. 2019 Jul-Sep;7(3):117-123. doi: 10.4103/JMAU.JMAU_12_19. PMID:31548922
- Saini S, Kaur C, Pal I, Kumar P, Jacob TG, Thakar A, Roy KK, Roy TS. Morphological development of the human cochlear nucleus. Hear Res. 2019 Oct; 382:107784. doi: 10.1016/j.heares.2019.107784. Epub 2019 Aug 20. PMID:31522073
- Kaur C, Saini S, Pal I, Kumar P, Sati HC, Jacob TG, Bhardwaj DN, Roy TS. Age-related changes in the number of cresyl-violet-stained, parvalbumin and NMDAR 2B expressing neurons in the human spiral ganglion. Hearing Res. 2020. https://doi.org/10.1016/j.heares. 2020.107883
- Kumar A, Faiq MA, Krishna H, Raj GV, Kishan V, Coffey JC, Jacob TG. Development of a Novel Technique to Dissect the Mesentery that Preserves Mesenteric Continuity and Enables Characterization of the Ex Vivo Mesentery. Front. Surg. 2020. doi: 10.3389/fsurg.2019.00080
- Ahuja R, Sharma N, Vashisht P, Jacob TG, Narang R, Bhatnagar N. Biocompatibility Analysis of PLA based Candidate Materials for Cardiovascular Stents in a Rat Subcutaneous Implant Model. Acta Histochemica. 2020;122(7):151615. doi: 10.1016/j.acthis.2020.151615
- Raghav R, Jain R, Jacob TG, Dhawan A, Roy TS. Co-administration of nalbuphine attenuates the morphine-induced anxiety and dopaminergic alterations in morphine-withdrawn rats. Psychopharmacology (Berl). 2021 Apr;238(4):1193-1211. doi: 10.1007/s00213-021-05765-3
- Nag HL, Jain G, Vijayakumar V, Jacob TG, Sonai M, Lalwani S. Femoral Intercondylar Notch: Gross Anatomy and Histology of the Connective Tissue Lining of its Roof: A Pilot Study. Surg Rad Anat. 2021. doi.org/10.1007/s00276-021-02757-y.
- Kumar P, Sharma S, Kaur C, Pal I, Bhardwaj DN, Vanamail P, Roy TS, Jacob TG. The ultrastructural study of human cochlear nerve at different ages. Hearing Research 2022. (in press). https://doi.org/10.1016/j.heares.2022.108443
- M. Uppal, T.G. Jacob, H.N. Yadav, S.K. Datta, R. Yadav, S.J. Mahapatra, P. Garg, P. Sahni, Therapeutic Methylprednisolone and Infimab Decrease the Severity of Organ Dysfunction in Pancreatic Duct Ligation Model of Severe Acute Pancreatitis in Wistar Rats, HPB, Volume Supplement 3, 2021, Page S739, ISSN 1365-182X, https://doi.org/10.1016/j.hpb.2021.08.136.
- Sharma MK, Priyam K, Kumar P, Garg PK, Roy TS, Jacob TG. Effect of calorie-restriction and rapamycin on autophagy and the severity of caerulein-induced experimental acute pancreatitis in mice. Front. Gastro (Therapy in Gastroenterology). 2022. Accepted for publication.

Dr.
Saroj Kaler
M.B.B.S.
Affiliation
Assistant Professor
Department of
Anatomy
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Dr. Saroj Kaler Jhajhria joined as assistant professor in the Anatomy department (AIIMS) in 2012. She did her M.B.B.S. from S.M.S. Medical College, Jaipur (Rajasthan). She completed MD and senior residency in Anatomy from the All India Institute of Medical Sciences (AIIMS), Delhi in 2008 and 2011 respectively. She is an active participant for Medical Education workshops & seminars and cadaveric workshops. Her interest includes neurobiology, toxicology and gross anatomy. She has administrative charge of the Gross Anatomy Lab (Dissection Hall)
- Kaler S, Gupta S, Prasoon P, Gautam M, Ray SB. Role of calcitonin gene-related peptide in nociception resulting from hind paw incision in rats. J Anat Soc India 2017; 66: 7–14
- Banerjee A, Kumari C, Kaler S. Variation in the branching pattern of third part of Axillary artery- A Case Report. J Clin Diagn Res 2017; 11 (2): 3- 41.
- Kumari C, Motwani R, Kaler S, Rani N, Jain P, Raza K, Dhawan V, Singh S. Higher Right Kidney and Partial Duplication of Left Ureter. Int. J Anat Res 2017; 5: 3788-3790
- Gautam M, Prasoon P, Kumar R, Reeta KH, Kaler S, Ray SB. Role of neurokinin type 1 receptor in nociception at the periphery and the spinal level in the rat. Spinal cord-Nature 2016; 54: 172-182
- Prasoon P, Gupta S, Kumar R, Gautam M, Kaler S, Ray SB. Role of fosaprepitant, a neurokinin Type 1 receptor antagonist, in morphine‑induced antinociception in Rats. Ind J Pharmacol 2016; 48 (4): 394-398

Prof.
Ritu Sehgal
MS Anatomy
Affiliation
Professor
Department of
Anatomy
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Additional Responsibility
receptors expression in breast cancer and medical education
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Dr. Ritu Sehgal graduated from Maulana Azad Medical College (MAMC) and completed her MS Anatomy and Senior Residency from the same institution. She was awarded the ‘Pyare Lal Sharma & Bishan Devi Gold Medal’ for Best thesis/student in Pre & Paraclinical Subjects. She joined AIIMS as Assistant Professor of Anatomy after working for a brief period as Assistant Professor at VMMC, New Delhi
- Kumar A, Sehgal R, Roy TS. A morphometric analysis and study of variations of foramina in the floor of the middle cranial fossa. J Anat Soc India 2016; 65(2): 143-147.
- Deshmukh VR, Singh S, Sehgal R. Cysto-duodeno-colic ligament and its clinical relevance. Biomed J 2016; 39(6): 414-416.

Prof.
T.C. Nag
Affiliation
Professor
Department of
Anatomy
Contact
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Additional Responsibility
Age-related structural and neurochemical changes in the human retina and factors associated with them, and the impact of iron accumulation through aging, and various effects of exposure to bright prolonged light on the retina in animal models (chicks and rodents).
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Dr TC Nag received his doctoral degree (1991) from the University of Calcutta, Kolkata. He was a postdoctoral fellow in the Department of Biology, University of Montréal, Canada (1993) and later worked as a research associate and Pool Officer in Neurobiology Laboratory at the Department of Anatomy, AIIMS, New Delhi (1995-1998). He also worked as a lecturer in West Bengal Educational Service (1998-2001) after which he joined as an assistant professor in the electron microscopy section of the department (2001). He is a recipient of Shakuntala Amir Chand Prize of ICMR (1999), SS Parmar Foundation Award and JR Bhattacharjee Award of Indian Academy of Neurosciences and AIIMS Research excellence award (2015) and is a member of National Academy of Sciences, Allahabad and Associate Editor, Journal of Biochemical and Molecular Toxicology (Wiley).
- Gupta CL, Nag TC, Jha KA, Kathpalia P, Maurya M, Kumar P, Gupta S, Roy TS (2020) Changes in the inner retinal cells after intense and constant light exposure in Sprague-Dawley rats. Photochem Photobiol 96: 1061-1073.
- Nag TC, Kathpalia P, Wadhwa S (2020) Microtubule alterations may destabilize photoreceptor integrity: Age-related microtubule changes and pattern of expression of MAP-2, Tau and hyperphosphorylated Tau in aging human photoreceptor cells. Exp Eye Res 198:108153.
- Maurya M, Nag TC, Kumar P, Roy TS (2021) Expression patterns of iron regulatory proteins after intense light exposure in a cone-dominated retina. Mol Cell Biochem 476: 3483-3495.
- Nag TC (2021) Pathogenic mechanisms contributing to the vulnerability of aging human photoreceptor cells. Eye 35: 2917-2929.
- Nag TC, Gorla S, Kumari C, Roy TS (2021) Aging of the human choriocapillaris: Evidence that early pericyte damage can trigger endothelial changes. Exp Eye Res 212:108771.

Prof.
Renu Dhingra
PhD
Affiliation
Professor
Department of
Anatomy
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Dr Renu Dhingra joined BSc (Hons) Human Biology at AIIMS, then completed her MSc (Anatomy) at AIIMS, followed by a PhD. She further worked as a Senior Demonstrator in the Department of Anatomy, AIIMS. Later, she joined University College of Medical Sciences, New Delhi as a Lecturer and thereafter at Gulf Medical College Ajman, UAE. Subsequently, she joined the department of Anatomy at AIIMS as an Assistant Professor.
Her research interest is in placental biology. At present, she is working on ‘apoptotic, oxidative endoplasmic reticulum stress and angiogenetic markers in pre –eclampsia . Her current research also focuses on migration and invasion studies on trophoblastic cells. The laboratory has the infrastructure for handling cell lines, conducting in-vitro assays, apoptotic, cytotoxic assays and other molecular biology techniques like ELISA, Immunofluorescence, Western Blot and PCR.
She has established the Plastination laboratory in the department. The plastinated specimens serve as valuable adjuncts for teaching Anatomy to undergraduate and postgraduate students.
- Arora P, Dhingra R, Bhatla N, Sharma A. VEGF and sFlt-1 polymorphisms in Preeclampsia. Placenta 2016; 45: 118–119
- Arora P, Kshetrapal P, Bhatla N, Rani N, Mochan S, Gupta SK, Saxena S, Dhingra R. Matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase- 2 mRNA levels in early onset preeclampsia. Placenta 2017; 51:131-132
- Gupta SK, Bhatla N, Rani N, Mochan S, Saxena S, Arora P, Dhingra R. Hydrogen sulphide producing enzymes are decreased in placentas from preeclampsia. Placenta. 2017; 51: 131.
- Mochan S, Bhatla N, Rani N, Gupta SK, Saxena S, Arora P, Dhingra R. SFLT-1 induces endoplasmic reticulum stress by activating perk pathway in bewo cells Placenta. 2017; 51: 131.

Prof.
Arundhati Sharma
M. Sc, B. Sc
Affiliation
Professor
Department of
Anatomy
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Prof. Arundhati Sharma did her graduation (B. Sc) and post graduation (M. Sc) in Genetics and Molecular Biology from Osmania and Pune University, respectively. She did her Ph D in Human Genetics from Nizam’s Institute of Medical Sciences and did her subsequent post doctoral work in the Department of Medical Genetics, SGPGIMS, Lucknow. Later, she joined as Assistant Professor of Genetics in the Department of Anatomy, AIIMS. Her work includes teaching, training and providing diagnostic facilities in the field of Human genetics. Her laboratory provides the following:
Diagnostic and patient care services- conventional cytogenetic services (Karyotyping) and other chromosomal studies. Molecular cytogenetic services using fluorescent in-situ hybridization (FISH) for various genetic numerical and structural abnormalities, cancers and other genetic conditions. Research interests include genetics of various endocrine and eye disorders, identification of biomarkers for prognostic and diagnostic purposes for various cancers and adverse drug reactions, and studies of Addiction genetics, i.e. identification of the genetic contribution to alcohol and drug dependence.
- Marik B, Bagga A , Sinha A , Khandelwal P , Hari P , Sharma A. Genetic and clinical profile of patients with hypophosphatemic rickets. Eur J Med Gen 21 June 2022. https://doi.org/10.1016/j.ejmg.2022.104540.
- Vanathi M, Kishore A, Gupta Y, Setty PB, Sen S, Nag TC, Gupta R, Sharma A, Tandon R. Recurrence in Reis Bücklers corneal dystrophy: Clinicopathological correlation. Indian J Ophthalmol Case Rep 2022; 2:371-5.
- Chakraborty S, Sharma A, Bagchi I, Pal S, Bhattacharyya C, Gupta V, Maitra A, Bhattacharjee S, Sharma A, Sihota R, Acharya M. A genomewide association study on individuals with occludable angles identifies potential risk loci for intraocular pressure. J Genet. 2021;100:69. PMID: 34608871
- Sarkar S, Singh R, Sharma A, Pandit MA, Gupta R, Singhal D, Jain R, Balhara YP. Association of Serotonergic Pathway Gene Polymorphisms With Behavioral Parameters in Patients With Opioid Dependence. Cureus. 2021 Nov 6;13(11):e19310. doi: 10.7759/cureus.19310. PMID: 34900485; PMCID: PMC8647861
- Gupta V, Somarajan BI, Kaur G, Gupta S, Singh R, Pradhan D, Singh H, Kaur P, Sharma A, Chawla B, Pahuja A, Ramachandran R, Sharma A. Exome sequencing identifies procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 mutations in primary congenital and juvenile glaucoma. Indian J Ophthalmol. 2021 Oct;69(10):2710-2716. doi: 10.4103/ijo.IJO_1750_21. PMID: 34571620; PMCID: PMC8597539.
- Gupta V, Somarajan BI, Gupta S, Walia GK, Singh A, Sofi R, Chaudhary RS, Sharma A. The mutational spectrum of Myocilin gene among familial versus sporadic cases of Juvenile onset open angle glaucoma. Eye (Lond). 2021;35(2):400-408.
- Grover T, Gupta R, Arora G, Bal CS, Ambekar A, Ray SB, Vaswani M, Sharma A. Dopamine transporter availability in alcohol and opioid dependent subjects – a 99mTc-TRODAT1SPECT imaging and genetic association study. Psychiatry Res Neuroimaging. 2020; 305:111187. doi: 10.1016/j.pscychresns.2020.111187. Online ahead of print.

Ms.
Srishty Raman
PhD
Affiliation
PhD
Department of
Anatomy
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Mr.
Mahesh Dutt
Affiliation
Technical Officer
Department of
Anatomy
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Mr.
Arvind Dabas
Affiliation
Technical Officer
Department of
Anatomy
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Mr.
Bhupinder Kumar
Affiliation
Sr. Technical Officer
Department of
Anatomy
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